| Gene Symbol |
RNMTL1
|
| Entrez Gene |
55178
|
| Alt Symbol |
HC90, MRM3, RMTL1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
RNA methyltransferase like 1
|
| Other Description |
16S rRNA (guanosine(1370)-2'-O)-methyltransferase|16S rRNA [Gm1370] 2'-O-methyltransferase|RNA methyltransferase-like protein 1|putative RNA methyltransferase|rRNA methyltransferase 3, mitochondrial
|
| Swissprots |
Q9NVQ5 Q9HC36 Q53GN1 Q96F76 Q86VC3
|
| Accessions |
EAW90642 Q9HC36 AF177344 AAG17988 AK001443 BAA91694 AK222900 BAD96620 AK225128 BC011550 AAH11550 BC050614 AAH50614 HQ448718 ADQ33196 XM_006721553 XP_006721616 NM_018146 NP_060616
|
| Function |
S-adenosyl-L-methionine-dependent 2'-O-ribose methyltransferase that catalyzes the formation of 2'-O- methylguanosine at position 1370 (Gm1370) in the 16S mitochondrial large subunit ribosomal RNA (mtLSU rRNA), a conserved modification in the peptidyl transferase domain of the mtLSU rRNA. {ECO:0000269|PubMed:24036117, ECO:0000269|PubMed:25009282, ECO:0000269|PubMed:25074936}.
|
| Subcellular Location |
Mitochondrion {ECO:0000269|PubMed:24036117, ECO:0000269|PubMed:25009282}.
|
| Tissue Specificity |
Expressed at same level in normal liver and hepatocarcinoma. {ECO:0000269|PubMed:12296377}.
|