Gene Symbol | RNMTL1 |
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Entrez Gene | 55178 |
Alt Symbol | HC90, MRM3, RMTL1 |
Species | Human |
Gene Type | protein-coding |
Description | RNA methyltransferase like 1 |
Other Description | 16S rRNA (guanosine(1370)-2'-O)-methyltransferase|16S rRNA [Gm1370] 2'-O-methyltransferase|RNA methyltransferase-like protein 1|putative RNA methyltransferase|rRNA methyltransferase 3, mitochondrial |
Swissprots | Q9NVQ5 Q9HC36 Q53GN1 Q96F76 Q86VC3 |
Accessions | EAW90642 Q9HC36 AF177344 AAG17988 AK001443 BAA91694 AK222900 BAD96620 AK225128 BC011550 AAH11550 BC050614 AAH50614 HQ448718 ADQ33196 XM_006721553 XP_006721616 NM_018146 NP_060616 |
Function | S-adenosyl-L-methionine-dependent 2'-O-ribose methyltransferase that catalyzes the formation of 2'-O- methylguanosine at position 1370 (Gm1370) in the 16S mitochondrial large subunit ribosomal RNA (mtLSU rRNA), a conserved modification in the peptidyl transferase domain of the mtLSU rRNA. {ECO:0000269|PubMed:24036117, ECO:0000269|PubMed:25009282, ECO:0000269|PubMed:25074936}. |
Subcellular Location | Mitochondrion {ECO:0000269|PubMed:24036117, ECO:0000269|PubMed:25009282}. |
Tissue Specificity | Expressed at same level in normal liver and hepatocarcinoma. {ECO:0000269|PubMed:12296377}. |
RNMTL1 CRISPR/Cas9 KO Plasmid (h) - sc-412471 from Santa Cruz Biotechnology
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RNMTL1 HDR Plasmid (h) - sc-412471-HDR from Santa Cruz Biotechnology
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RNMTL1 Double Nickase Plasmid (h) - sc-412471-NIC from Santa Cruz Biotechnology
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RNMTL1 Double Nickase Plasmid (h2) - sc-412471-NIC-2 from Santa Cruz Biotechnology
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RNMTL1 CRISPR Activation Plasmid (h) - sc-412471-ACT from Santa Cruz Biotechnology
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RNMTL1 CRISPR Activation Plasmid (h2) - sc-412471-ACT-2 from Santa Cruz Biotechnology
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RNMTL1 Lentiviral Activation Particles (h) - sc-412471-LAC from Santa Cruz Biotechnology
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RNMTL1 Lentiviral Activation Particles (h2) - sc-412471-LAC-2 from Santa Cruz Biotechnology
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RNMTL1 siRNA (h) - sc-93988 from Santa Cruz Biotechnology
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RNMTL1 shRNA Plasmid (h) - sc-93988-SH from Santa Cruz Biotechnology
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RNMTL1 shRNA (h) Lentiviral Particles - sc-93988-V from Santa Cruz Biotechnology
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RNMTL1 RNAi - H00055178-R01 from Novus Biologicals
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MISSION® esiRNA - EHU136271 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN18451 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18451 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03613 from Sigma-Aldrich
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RNMTL1 siRNA (Human) - CRJ0531 from Cohesion Biosciences
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RNMTL1 - MBS8222606 from MyBioSource
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shRNA set against Human RNMTL1 (NM_018146.2) - SHH397512 from Creative biogene
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shRNA set against Human RNMTL1(NM_018146.2) - SHR188886 from Creative biogene
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Human RNMTL1 siRNA - orb271032 from Biorbyt
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RNMTL1 shRNA Plasmid (Human) - CHJ0531 from Cohesion Biosciences
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RNMTL1 miRNA 3'UTR clone - MiUTR1H-08914 from Creative biogene
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