| Gene Symbol |
DCAF12
|
| Entrez Gene |
25853
|
| Alt Symbol |
CT102, KIAA1892, TCC52, WDR40A
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
DDB1 and CUL4 associated factor 12
|
| Other Description |
DDB1- and CUL4-associated factor 12|WD repeat domain 40A|WD repeat-containing protein 40A|cancer/testis antigen 102|centrosome-related protein TCC52|testis cancer centrosome-related protein
|
| Swissprots |
A8KA70 Q9NXA9 Q5T6E9 Q7L4F8 Q6P3V0 Q5T6F1 Q5T6F0 Q96PZ5 Q9UFJ1 D3DRL6
|
| Accessions |
EAW58472 EAW58473 EAW58474 Q5T6F0 AB067479 BAB67785 AF085907 AF131771 AI140359 AK000354 BAA91106 AK292935 BAF85624 AL117646 CAB56028 BC008893 AAH08893 BC063823 AAH63823 BC127177 BG718613 BM144957 BM194397 BM747928 DQ518909 ABG24246 XM_006716752 XP_006716815 XM_011517843 XP_011516145 NM_015397 NP_056212
|
| Function |
May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex. {ECO:0000269|PubMed:16949367, ECO:0000269|PubMed:16964240}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:18957058}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:18957058}.
|
| Tissue Specificity |
Highly expressed in lung cancer tissues and some cancer cell lines. Restricted expression in normal testis. {ECO:0000269|PubMed:18957058}.
|