Gene Symbol | DCAF12 |
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Entrez Gene | 25853 |
Alt Symbol | CT102, KIAA1892, TCC52, WDR40A |
Species | Human |
Gene Type | protein-coding |
Description | DDB1 and CUL4 associated factor 12 |
Other Description | DDB1- and CUL4-associated factor 12|WD repeat domain 40A|WD repeat-containing protein 40A|cancer/testis antigen 102|centrosome-related protein TCC52|testis cancer centrosome-related protein |
Swissprots | A8KA70 Q9NXA9 Q5T6E9 Q7L4F8 Q6P3V0 Q5T6F1 Q5T6F0 Q96PZ5 Q9UFJ1 D3DRL6 |
Accessions | EAW58472 EAW58473 EAW58474 Q5T6F0 AB067479 BAB67785 AF085907 AF131771 AI140359 AK000354 BAA91106 AK292935 BAF85624 AL117646 CAB56028 BC008893 AAH08893 BC063823 AAH63823 BC127177 BG718613 BM144957 BM194397 BM747928 DQ518909 ABG24246 XM_006716752 XP_006716815 XM_011517843 XP_011516145 NM_015397 NP_056212 |
Function | May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex. {ECO:0000269|PubMed:16949367, ECO:0000269|PubMed:16964240}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:18957058}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:18957058}. |
Tissue Specificity | Highly expressed in lung cancer tissues and some cancer cell lines. Restricted expression in normal testis. {ECO:0000269|PubMed:18957058}. |
WDR40A CRISPR/Cas9 KO Plasmid (h) - sc-411813 from Santa Cruz Biotechnology
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WDR40A HDR Plasmid (h) - sc-411813-HDR from Santa Cruz Biotechnology
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WDR40A Double Nickase Plasmid (h) - sc-411813-NIC from Santa Cruz Biotechnology
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WDR40A Double Nickase Plasmid (h2) - sc-411813-NIC-2 from Santa Cruz Biotechnology
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WDR40A CRISPR Activation Plasmid (h) - sc-411813-ACT from Santa Cruz Biotechnology
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WDR40A CRISPR Activation Plasmid (h2) - sc-411813-ACT-2 from Santa Cruz Biotechnology
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WDR40A Lentiviral Activation Particles (h) - sc-411813-LAC from Santa Cruz Biotechnology
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WDR40A Lentiviral Activation Particles (h2) - sc-411813-LAC-2 from Santa Cruz Biotechnology
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WDR40A siRNA (h) - sc-92817 from Santa Cruz Biotechnology
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WDR40A shRNA Plasmid (h) - sc-92817-SH from Santa Cruz Biotechnology
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WDR40A shRNA (h) Lentiviral Particles - sc-92817-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU100761 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN6959 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6959 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR10859 from Sigma-Aldrich
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DCAF12 siRNA (Human) - CRH8545 from Cohesion Biosciences
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DCAF12 - MBS8217540 from MyBioSource
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shRNA set against Human DCAF12 (NM_015397.3) - SHH274877 from Creative biogene
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Human DCAF12 siRNA - orb269047 from Biorbyt
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DCAF12 shRNA Plasmid (Human) - CHH8545 from Cohesion Biosciences
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DCAF12 miRNA 3'UTR clone - MiUTR3H-14597 from Creative biogene
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