| Gene Symbol |
WDR62
|
| Entrez Gene |
284403
|
| Alt Symbol |
C19orf14, MCPH2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
WD repeat domain 62
|
| Other Description |
WD repeat-containing protein 62|microcephaly, primary autosomal recessive 2
|
| Swissprots |
Q659D7 Q8NBF7 O43379 Q63HP9 Q96AD9
|
| Accessions |
AAC27979 O43379 AK090617 BAC03488 AL041673 AL117438 CAB55924 AL133651 CAH56390 AW029580 BC017261 AAH17261 BC058939 BC128417 AAI28418 BC151839 BQ880028 BQ960310 BU508347 BX647726 CAH56191 CF142643 JF432250 ADZ15467 XM_005258809 XP_005258866 XM_011526837 XP_011525139 XM_011526838 XP_011525140 XM_011526839 XP_011525141 XM_011526840 XP_011525142 XM_011526841 XP_011525143 XM_011526842 XP_011525144 XM_011526843 XP_011525145 XM_011526844 XP_011525146 NM_001083961 NP_001077430 NM_173636 NP_775907
|
| Function |
Required for cerebral cortical development. Plays a role in neuronal proliferation and migration. {ECO:0000269|PubMed:20729831, ECO:0000269|PubMed:20890278}.
|
| Subcellular Location |
Nucleus. Cytoplasm, cytoskeleton, spindle pole. Note=Shows cell cycle-dependent localization. Accumulates to the spindle pole during mitosis.
|
| Tissue Specificity |
Present in fetal brain, enriched within the ventricular and subventricular zone (at protein level). In the embryonic brain it is expressed in mitotic neural precursor cells. {ECO:0000269|PubMed:20890279}.
|