| Gene Symbol |
CD3EAP
|
| Entrez Gene |
10849
|
| Alt Symbol |
ASE-1, ASE1, CAST, PAF49
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
CD3e molecule, epsilon associated protein
|
| Other Description |
CD3e antigen, epsilon polypeptide associated protein|DNA-directed RNA polymerase I subunit RPA34|RNA polymerase I-associated factor PAF49|antisense to ERCC-1 protein
|
| Swissprots |
O15446 Q9UPF6 Q7Z5U2 Q32N11
|
| Accessions |
EAW57346 EAW57347 O15446 AF017633 AAD41158 AK292183 BAF84872 BC009705 AAH09705 BC028109 BC038992 AAH38992 BC046141 AAH46141 BC054044 AAH54044 BC065251 BC108889 AAI08890 BU166593 EU446938 ABZ92467 U86751 AAB68608 NM_001297590 NP_001284519 NM_012099 NP_036231
|
| Function |
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors. Isoform 1 is involved in UBTF-activated transcription, presumably at a step following PIC formation.
|
| Subcellular Location |
Nucleus, nucleolus {ECO:0000269|PubMed:9426281}. Chromosome {ECO:0000269|PubMed:9426281}. Note=Found at the fibrillar centers of the nucleolus in interphase and during cell division it is localized to the nucleolus organizer regions of the chromosomes.
|
![Western Blot: PAF49 Overexpression Lysate (Adult Normal) [NBL1-08945] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for PAF49.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/3610_PAF49%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-08945-img0002.jpg)