Gene Symbol | CD3EAP |
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Entrez Gene | 10849 |
Alt Symbol | ASE-1, ASE1, CAST, PAF49 |
Species | Human |
Gene Type | protein-coding |
Description | CD3e molecule, epsilon associated protein |
Other Description | CD3e antigen, epsilon polypeptide associated protein|DNA-directed RNA polymerase I subunit RPA34|RNA polymerase I-associated factor PAF49|antisense to ERCC-1 protein |
Swissprots | O15446 Q9UPF6 Q7Z5U2 Q32N11 |
Accessions | EAW57346 EAW57347 O15446 AF017633 AAD41158 AK292183 BAF84872 BC009705 AAH09705 BC028109 BC038992 AAH38992 BC046141 AAH46141 BC054044 AAH54044 BC065251 BC108889 AAI08890 BU166593 EU446938 ABZ92467 U86751 AAB68608 NM_001297590 NP_001284519 NM_012099 NP_036231 |
Function | DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors. Isoform 1 is involved in UBTF-activated transcription, presumably at a step following PIC formation. |
Subcellular Location | Nucleus, nucleolus {ECO:0000269|PubMed:9426281}. Chromosome {ECO:0000269|PubMed:9426281}. Note=Found at the fibrillar centers of the nucleolus in interphase and during cell division it is localized to the nucleolus organizer regions of the chromosomes. |
CD3EAP CRISPR/Cas9 KO Plasmid (h) - sc-411524 from Santa Cruz Biotechnology
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CD3EAP HDR Plasmid (h) - sc-411524-HDR from Santa Cruz Biotechnology
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CD3EAP Double Nickase Plasmid (h) - sc-411524-NIC from Santa Cruz Biotechnology
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CD3EAP Double Nickase Plasmid (h2) - sc-411524-NIC-2 from Santa Cruz Biotechnology
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CD3EAP CRISPR Activation Plasmid (h) - sc-411524-ACT from Santa Cruz Biotechnology
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CD3EAP CRISPR Activation Plasmid (h2) - sc-411524-ACT-2 from Santa Cruz Biotechnology
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CD3EAP Lentiviral Activation Particles (h) - sc-411524-LAC from Santa Cruz Biotechnology
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CD3EAP Lentiviral Activation Particles (h2) - sc-411524-LAC-2 from Santa Cruz Biotechnology
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CD3EAP siRNA (h) - sc-72829 from Santa Cruz Biotechnology
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CD3EAP shRNA Plasmid (h) - sc-72829-SH from Santa Cruz Biotechnology
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CD3EAP shRNA (h) Lentiviral Particles - sc-72829-V from Santa Cruz Biotechnology
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PAF49 RNAi - H00010849-R01 from Novus Biologicals
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MISSION® esiRNA - EHU149981 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN5728 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5728 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR08750 from Sigma-Aldrich
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CD3EAP siRNA (Human) - CRH7389 from Cohesion Biosciences
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CD3EAP - MBS8220439 from MyBioSource
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shRNA set against Human CD3EAP (NM_012099.1) - SHH259069 from Creative biogene
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CD3EAP shRNA Plasmid (Human) - CHH7389 from Cohesion Biosciences
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CD3EAP miRNA 3'UTR clone - MiUTR1H-01876 from Creative biogene
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