| Gene Symbol |
RBM14
|
| Entrez Gene |
10432
|
| Alt Symbol |
COAA, PSP2, SIP, SYTIP1, TMEM137
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
RNA binding motif protein 14
|
| Other Description |
RNA-binding protein 14|RRM-containing coactivator activator/modulator|SYT-interacting protein|paraspeckle protein 2|synaptotagmin-interacting protein|transmembrane protein 137
|
| Swissprots |
Q53GV1 O75932 B0LM41 Q96PK6 B3KMN4 Q68DQ9 Q96PK5 D6RGD8 Q2PYN1
|
| Accessions |
EAW74552 EAW74553 Q96PK6 AB209007 BAD92244 AF080561 AAC64058 AF315632 AAK77961 AF315633 AAK77962 AK021768 BAG51046 AK222830 BAD96550 AK297907 BAG60226 AK307254 BC000488 AAH00488 BC007641 AAH07641 BC023619 BC024260 AAH24260 CR749306 CAH18161 DB044990 DQ294957 ABB99396 EU446504 ABZ92033 NM_001198836 NP_001185765 NM_001198837 NP_001185766 NM_006328 NP_006319 NM_032886
|
| Function |
Isoform 1 may function as a nuclear receptor coactivator, enhancing transcription through other coactivators such as NCOA6 and CITED1. Isoform 2, functions as a transcriptional repressor, modulating transcriptional activities of coactivators including isoform 1, NCOA6 and CITED1.
|
| Subcellular Location |
Nucleus. Nucleus, nucleolus. Note=In punctate subnuclear structures often located adjacent to splicing speckles, called paraspeckles.
|
| Tissue Specificity |
Expressed in all tissues tested, including brain, heart, skeletal muscle, colon, thymus, spleen, kidney, liver, small intestine, placenta, lung and peripheral blood lymphocytes.
|
![Western Blot: RBM14 Overexpression Lysate (Adult Normal) [NBP2-07626] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for RBM14.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/8460_RBM14%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-07626-img0001.jpg)