Gene Symbol | RBM14 |
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Entrez Gene | 10432 |
Alt Symbol | COAA, PSP2, SIP, SYTIP1, TMEM137 |
Species | Human |
Gene Type | protein-coding |
Description | RNA binding motif protein 14 |
Other Description | RNA-binding protein 14|RRM-containing coactivator activator/modulator|SYT-interacting protein|paraspeckle protein 2|synaptotagmin-interacting protein|transmembrane protein 137 |
Swissprots | Q53GV1 O75932 B0LM41 Q96PK6 B3KMN4 Q68DQ9 Q96PK5 D6RGD8 Q2PYN1 |
Accessions | EAW74552 EAW74553 Q96PK6 AB209007 BAD92244 AF080561 AAC64058 AF315632 AAK77961 AF315633 AAK77962 AK021768 BAG51046 AK222830 BAD96550 AK297907 BAG60226 AK307254 BC000488 AAH00488 BC007641 AAH07641 BC023619 BC024260 AAH24260 CR749306 CAH18161 DB044990 DQ294957 ABB99396 EU446504 ABZ92033 NM_001198836 NP_001185765 NM_001198837 NP_001185766 NM_006328 NP_006319 NM_032886 |
Function | Isoform 1 may function as a nuclear receptor coactivator, enhancing transcription through other coactivators such as NCOA6 and CITED1. Isoform 2, functions as a transcriptional repressor, modulating transcriptional activities of coactivators including isoform 1, NCOA6 and CITED1. |
Subcellular Location | Nucleus. Nucleus, nucleolus. Note=In punctate subnuclear structures often located adjacent to splicing speckles, called paraspeckles. |
Tissue Specificity | Expressed in all tissues tested, including brain, heart, skeletal muscle, colon, thymus, spleen, kidney, liver, small intestine, placenta, lung and peripheral blood lymphocytes. |
RBM14 CRISPR/Cas9 KO Plasmid (h) - sc-417972 from Santa Cruz Biotechnology
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RBM14 HDR Plasmid (h) - sc-417972-HDR from Santa Cruz Biotechnology
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RBM14 Double Nickase Plasmid (h) - sc-417972-NIC from Santa Cruz Biotechnology
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RBM14 Double Nickase Plasmid (h2) - sc-417972-NIC-2 from Santa Cruz Biotechnology
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RBM14 CRISPR Activation Plasmid (h) - sc-417972-ACT from Santa Cruz Biotechnology
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RBM14 CRISPR Activation Plasmid (h2) - sc-417972-ACT-2 from Santa Cruz Biotechnology
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RBM14 Lentiviral Activation Particles (h) - sc-417972-LAC from Santa Cruz Biotechnology
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RBM14 Lentiviral Activation Particles (h2) - sc-417972-LAC-2 from Santa Cruz Biotechnology
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RBM14 siRNA (h) - sc-96838 from Santa Cruz Biotechnology
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RBM14 shRNA Plasmid (h) - sc-96838-SH from Santa Cruz Biotechnology
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RBM14 shRNA (h) Lentiviral Particles - sc-96838-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU108601 from Sigma-Aldrich
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MISSION® esiRNA - EHU014081 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN18026 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18026 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR06107 from Sigma-Aldrich
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RBM14 siRNA (Human) - CRH7075 from Cohesion Biosciences
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RBM14 RNAi - H00010432-R01 from Novus Biologicals
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RBM14 - MBS8233441 from MyBioSource
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shRNA set against Human RBM14 (NM_006328.3) - SHH390536 from Creative biogene
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Human RBM14 siRNA - orb267577 from Biorbyt
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RBM14 shRNA Plasmid (Human) - CHH7075 from Cohesion Biosciences
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RBM14 miRNA 3'UTR clone - MiUTR4H-TG07374 from Creative biogene
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