ORC3

Gene Symbol ORC3
Entrez Gene 23595
Alt Symbol LAT, LATHEO, ORC3L
Species Human
Gene Type protein-coding
Description origin recognition complex, subunit 3
Other Description homolog of latheo, Drosophila|origin recognition complex subunit 3|origin recognition complex subunit Latheo|origin recognition complex, subunit 3 honolog
Swissprots Q6IUY7 Q5T159 Q53GY6 A2A2T5 Q9UNT6 Q9UG44 Q13565 Q86TN5 Q9UBD5 B4E025
Accessions AAT38109 EAW48581 EAW48582 EAW48583 Q9UBD5 AF093535 AAD40220 AF125507 AAD18057 AF135044 AAD30282 AK094135 AK222795 BAD96515 AK302750 BAG63963 AK303056 BAH13891 AK303182 BAG64276 AK303195 BAG64287 AK315911 BAH14282 AK316298 BAH14669 AL080116 CAB45715 BC035494 AAH35494 BC047689 AAH47689 BF215571 BM971022 CR456814 CAG33095 DC395106 EU446990 ABZ92519 EU831634 ACE87234 U50950 AAA96313 XM_005248704 XP_005248761 XM_005248705 XP_005248762 XM_005248706 XP_005248763 XM_011535651 XP_011533953 XM_011535652 XP_011533954 XR_942370 NM_001197259 NP_001184188 NM_012381 NP_036513 NM_181837 NP_862820
Function Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre- replication complex necessary to initiate DNA replication. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K27me3 and H4K20me3. {ECO:0000269|PubMed:22427655}.
Subcellular Location Nucleus.
Top Pathways Cell cycle

ORC3 (H-97) - sc-98930 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

ORC3 (C-12) - sc-374231 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
ORC3 (C-12): sc-374231. Western blot analysis of ORC3 expression in HeLa (A) and Jurkat (B) whole cell lysates.

ORC3 (1D6) - sc-23888 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rat
Clonality Monoclonal
ORC3 (1D6): sc-23888. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human ovary tissue showing nuclear localization.

ORC3 (G-20) - sc-30957 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

ORC3 (K-17) - sc-21862 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

ORC3 (T-13) - sc-21863 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-ORC3 antibody - ab123550 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-ORC3 antibody (ab123550) at 1/100 dilution + HeLa cell line lysates at 35 µg

Anti-ORC3 antibody - ab188008 from Abcam

Prices $443.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin-embedded Human stomach, lower tissue labeling ORC3 with ab188008 at 1/1000 dilution.

Anti-ORC3L antibody - ab9213 from Abcam

Prices $370.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-ORC3L antibody - ab99278 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human breast carcinoma tissue labelling ORC3L with ab99278 at 1/200 (1µg/mg). Detection: DAB.

Anti-ORC3L antibody [1D6] - ab22531 from Abcam

Prices $370.00
Sizes 50 µl
Host Rat
Clonality Monoclonal
Clone 1D6

Anti-ORC3L / ORC3 Antibody (aa17-46, FITC) - LS-C223557 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ORC3L / ORC3 Antibody (aa17-46, Azide-free, HRP) - LS-C223558 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ORC3L / ORC3 Antibody (aa17-46, PE) - LS-C223559 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ORC3L / ORC3 Antibody (aa16-46) - LS-C323699 from LifeSpan Bioscience

Prices $435.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ORC3L / ORC3 Antibody (clone 1G1) - LS-C139483 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1G1
Detection limit for recombinant GST tagged ORC3L is 0.03 ng/ml as a capture antibody.

Anti-ORC3L / ORC3 Antibody (C-Terminus) - LS-C145741 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ORC3 / ORC3L antibody LS-C145741 Western blot of HepG2 Cell lysate. Antibody concentration 1 ug/ml.

Anti-ORC3L / ORC3 Antibody (aa43-92) - LS-C145742 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ORC3 / ORC3L antibody LS-C145742 Western blot of HepG2 Cell lysate. Antibody concentration 1 ug/ml.

Anti-ORC3L / ORC3 Antibody (aa17-46) - LS-C163270 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
ORC3L Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human lung adenocarcinoma followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-ORC3L / ORC3 Antibody (aa325-375) - LS-C289455 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human ORC3 by Immunohistochemistry. Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti-ORC3 used at a dilution of 1:200 (1 ug/mg).

Anti-ORC3L / ORC3 Antibody (clone 1D6) - LS-C82307 from LifeSpan Bioscience

Prices $380.00
Sizes 50 µl
Host Rat
Clonality Monoclonal
Clone 1D6

Anti-ORC3L / ORC3 Antibody (aa17-46, AP) - LS-C223554 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ORC3L / ORC3 Antibody (aa17-46, APC) - LS-C223555 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ORC3L / ORC3 Antibody (aa17-46, Biotin) - LS-C223556 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ORC3L / ORC3 Antibody (aa699-712) IHC-plus™ - LS-B9179 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Human Brain, Cortex
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