Gene Symbol | CDCA7 |
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Entrez Gene | 83879 |
Alt Symbol | JPO1 |
Species | Human |
Gene Type | protein-coding |
Description | cell division cycle associated 7 |
Other Description | c-Myc target JPO1|cell division cycle associated protein 7|cell division cycle-associated protein 7 |
Swissprots | Q9BWT1 Q96BV8 Q8NBY9 Q658K4 Q96SP5 Q53EW5 B4DV66 Q580W9 B4DLP8 Q658N4 |
Accessions | AAX82003 EAX11158 EAX11159 EAX11160 EAX11161 Q9BWT1 AK027628 BAB55245 AK027642 BAB55258 AK075134 BAC11425 AK223524 BAD97244 AK297097 BAG59610 AK297245 BAG59725 AK300949 BAG62578 AL833728 CAH56253 AL834186 CAH56357 AY029179 AAK31591 BC015124 AAH15124 BC027966 AAH27966 DA531905 HQ447803 ADQ32287 XM_011511957 XP_011510259 XR_923034 NM_031942 NP_114148 NM_145810 NP_665809 |
Function | Participates in MYC-mediated cell transformation and apoptosis; induces anchorage-independent growth and clonogenicity in lymphoblastoid cells. Insufficient to induce tumorigenicity when overexpressed but contributes to MYC-mediated tumorigenesis. May play a role as transcriptional regulator. {ECO:0000269|PubMed:11598121, ECO:0000269|PubMed:15994934, ECO:0000269|PubMed:16580749, ECO:0000269|PubMed:23166294}. |
Subcellular Location | Nucleus. Cytoplasm. Note=Predominantly nuclear with some expression also seen in the cytoplasm. Predominantly cytoplasmic when phosphorylated at Thr-163. |
Tissue Specificity | Ubiquitous with higher level in thymus and small intestine. Overexpressed in a large number of tumors, in blood from patients with acute myelogenous leukemia (AML) and in chronic myelogenous leukemia (CML) blast crisis. {ECO:0000269|PubMed:11598121, ECO:0000269|PubMed:15994934}. |
CdcA7 (K-16) - sc-246238 from Santa Cruz Biotechnology
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CdcA7 (T-12) - sc-246237 from Santa Cruz Biotechnology
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Anti-CDCA7 antibody - ab69609 from Abcam
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Anti-CDCA7 Antibody (aa141-190) - LS-C119445 from LifeSpan Bioscience
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Anti-CDCA7 Antibody (aa58-107) - LS-C186817 from LifeSpan Bioscience
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CDCA7 Antibody - NBP1-82224 from Novus Biologicals
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CDCA7 Antibody - NBP2-15838 from Novus Biologicals
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CDCA7 Polyclonal Antibody - bs-9128R from Bioss
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Anti-CDCA7 antibody produced in rabbit - SAB4503307 from Sigma-Aldrich
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Anti-CDCA7 antibody produced in rabbit - HPA005565 from Sigma-Aldrich
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CDCA7 Antibody - N-terminal region (ARP66756_P050) - ARP66756_P050 from Aviva Systems Biology
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CDCA7 Antibody (OAAF02885) - OAAF02885 from Aviva Systems Biology
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CDCA7 antibody - orb226108 from Biorbyt
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CDCA7 Antibody - abx013938 from Abbexa
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CDCA7 Antibody - abx121338 from Abbexa
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CDCA7 / JPO1 antibody - 15249-1-AP from Acris Antibodies
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CDCA7 antibody - 15249-1-AP from Proteintech Group
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Anti-CdcA7 antibody - STJ92186 from St John's Laboratory Ltd
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CDCA7 Polyclonal Antibody - PA001100-C12176 from Syd Labs
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CDCA7 Antibody - 34194 from Signalway Antibody
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CDCA7 Antibody - E11-12176C from Enogene
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CDCA7 Antibody - C12176 from Assay Biotechnology
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Human CDCA7 Antibody - GWB-ASE071 from Genway Biotech
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CDCA7, Polyclonal Antibody - MBS2519972 from MyBioSource
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CDCA7 Antibody - EPP11383 from Elabscience
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