Gene Symbol | ILKAP |
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Entrez Gene | 80895 |
Alt Symbol | ILKAP2, ILKAP3, PP2C-DELTA |
Species | Human |
Gene Type | protein-coding |
Description | integrin-linked kinase-associated serine/threonine phosphatase |
Other Description | integrin-linked kinase associated phosphatase|integrin-linked kinase-associated serine/threonine phosphatase 2C|protein phosphatase 2c, delta isozyme |
Swissprots | Q9H0C8 B3KM39 |
Accessions | AAY24336 EAW71145 EAW71146 Q9H0C8 AK001043 BAG50851 AK055417 AL136850 CAB66784 AY024365 AAK07736 BC006576 AAH06576 BC035746 BC050422 CR533533 CAG38564 DQ892800 ABM83726 DQ896047 ABM87046 EU832279 ACE87536 EU832364 ACE86849 FJ491380 ACL54845 FJ491381 ACL54846 HQ658059 AEI30977 HQ658060 AEI30978 XM_005246106 XP_005246163 XM_006712784 XP_006712847 XM_011511946 XP_011510248 XR_923033 NM_030768 NP_110395 NM_176799 |
Function | Protein phosphatase that may play a role in regulation of cell cycle progression via dephosphorylation of its substrates whose appropriate phosphorylation states might be crucial for cell proliferation. Selectively associates with integrin linked kinase (ILK), to modulate cell adhesion and growth factor signaling. Inhibits the ILK-GSK3B signaling axis and may play an important role in inhibiting oncogenic transformation. {ECO:0000269|PubMed:14990992}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:11331582}. |
Tissue Specificity | Widely expressed. Highest levels expressed in striated muscle. Much lower levels evident in various smooth muscle tissues. {ECO:0000269|PubMed:11331582}. |
Human ILKAP full length protein - ab164306 from Abcam
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Human ILKAP protein fragment - ab164307 from Abcam
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ILKAP Antibody Blocking Peptide - LS-E8029 from LifeSpan Bioscience
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ILKAP Antibody Blocking Peptide - LS-E22761 from LifeSpan Bioscience
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ILKAP Antibody Blocking Peptide - LS-E6611 from LifeSpan Bioscience
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Recombinant Human ILKAP/PP2C delta Protein - H00080895-Q01 from Novus Biologicals
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Recombinant Human ILKAP/PP2C delta Protein - H00080895-P01 from Novus Biologicals
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ILKAP-AntibodyCenter-Blocking-peptide - BP19399c from Abgent, a WuXi AppTec company
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ILKAP-Antibody-Center-Blocking-peptide - BP5884c from Abgent, a WuXi AppTec company
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Human ILKAP protein - orb246371 from Biorbyt
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ILKAP - H00080895-P01-02 from Acris Antibodies
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ILKAP - H00080895-Q01-10 from Acris Antibodies
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ILKAP - H00080895-Q01-25 from Acris Antibodies
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ILKAP fusion protein - Ag8826 from Proteintech Group
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Recombinant Human ILKAP, His tagged - ILKAP-1126H from Creative Biomart
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Recombinant Human ILKAP, His-tagged - ILKAP-14217H from Creative Biomart
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ILKAP - PN201723 from Elabscience
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Human ILKAP Protein (His Tag) - 12697-H08H-20 from Sino Biological
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ILKAP (K71) Peptide - BS2359P from Bioworld Technology
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Recombinant Human Integrin-linked kinase-associated serine/threonine phosphatase 2C(ILKAP) - CSB-YP011686HU CSB-BP011686HU CSB-MP011686HU from Cusabio
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Recombinant human Integrin-linked kinase-associated serine/threonine phosphatase - CSB-EP011686HU from Cusabio
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ILKAP - TP301456 from Acris Antibodies
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Recombinant Human ILKAP Protein (His tag) - PKSH030793 from Elabscience
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ILKAP/PP2C delta Recombinant Protein Antigen - NBP1-85117PEP from Novus Biologicals
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ILKAP Peptide, Human - M34GP07623H from Creative Peptides
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