Gene Symbol | GCLM |
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Entrez Gene | 2730 |
Alt Symbol | GLCLR |
Species | Human |
Gene Type | protein-coding |
Description | glutamate-cysteine ligase, modifier subunit |
Other Description | GCS light chain|GSC light chain|gamma-ECS regulatory subunit|gamma-glutamylcysteine synthetase regulatory subunit|glutamate--cysteine ligase modifier subunit|glutamate--cysteine ligase regulatory subunit|glutamate-cysteine ligase (gamma-glutamylcysteine synthetase), regulatory (30.8kD)|glutamate-cysteine ligase modifier subunit delta2 alternative splicing|glutamate-cysteine ligase regulatory protein |
Swissprots | Q6FHC1 M5A959 D3DT45 A8K334 P48507 Q9NU74 Q9NPX9 |
Accessions | AAB93484 AAC24417 AAR29001 AAV28733 EAW73059 EAW73060 EAW73061 EAW73062 P48507 AB809606 BAN05309 AK290449 BAF83138 BC041809 AAH41809 BE269549 BE866085 BF031933 BF213407 BF219130 BF246042 BF513627 BF541340 BF541441 BF698337 BG291243 BG501583 BG547387 BI497338 BM468805 BM982562 BQ049850 BQ224592 BU600458 BU754400 C17598 C18245 C18878 C18959 C19097 CB114258 CB123306 CB128427 CK818048 CN272168 CN422503 CR541833 CAG46632 D63311 L35546 AAA65028 N53134 R69169 XM_005270754 XP_005270811 XM_011541261 XP_011539563 NM_001308253 NP_001295182 NM_002061 NP_002052 |
Tissue Specificity | In all tissues examined. Highest levels in skeletal muscle. |
Top Pathways | Glutathione metabolism |
γ-GCSm CRISPR/Cas9 KO Plasmid (h) - sc-418078 from Santa Cruz Biotechnology
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γ-GCSm HDR Plasmid (h) - sc-418078-HDR from Santa Cruz Biotechnology
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γ-GCSm Double Nickase Plasmid (h) - sc-418078-NIC from Santa Cruz Biotechnology
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γ-GCSm Double Nickase Plasmid (h2) - sc-418078-NIC-2 from Santa Cruz Biotechnology
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γ-GCSm CRISPR Activation Plasmid (h) - sc-418078-ACT from Santa Cruz Biotechnology
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γ-GCSm CRISPR Activation Plasmid (h2) - sc-418078-ACT-2 from Santa Cruz Biotechnology
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γ-GCSm Lentiviral Activation Particles (h) - sc-418078-LAC from Santa Cruz Biotechnology
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γ-GCSm Lentiviral Activation Particles (h2) - sc-418078-LAC-2 from Santa Cruz Biotechnology
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γ-GCSm siRNA (h) - sc-40602 from Santa Cruz Biotechnology
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γ-GCSm shRNA Plasmid (h) - sc-40602-SH from Santa Cruz Biotechnology
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γ-GCSm shRNA (h) Lentiviral Particles - sc-40602-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU027431 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN9192 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9192 from Sigma-Aldrich
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GCLM siRNA (Human) - CRH1815 from Cohesion Biosciences
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GCLM RNAi - H00002730-R01 from Novus Biologicals
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GCLM - MBS8222311 from MyBioSource
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shRNA set against Human GCLM (NM_002061.2) - SHH300058 from Creative biogene
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shRNA set against Human GCLM(NM_002061.2) - SHH080057 from Creative biogene
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Human GCLM siRNA - orb262317 from Biorbyt
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GCLM shRNA Plasmid (Human) - CHH1815 from Cohesion Biosciences
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GCLM miRNA 3'UTR clone - MiUTR1H-03987 from Creative biogene
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