GCLM

Gene Symbol GCLM
Entrez Gene 2730
Alt Symbol GLCLR
Species Human
Gene Type protein-coding
Description glutamate-cysteine ligase, modifier subunit
Other Description GCS light chain|GSC light chain|gamma-ECS regulatory subunit|gamma-glutamylcysteine synthetase regulatory subunit|glutamate--cysteine ligase modifier subunit|glutamate--cysteine ligase regulatory subunit|glutamate-cysteine ligase (gamma-glutamylcysteine synthetase), regulatory (30.8kD)|glutamate-cysteine ligase modifier subunit delta2 alternative splicing|glutamate-cysteine ligase regulatory protein
Swissprots Q6FHC1 M5A959 D3DT45 A8K334 P48507 Q9NU74 Q9NPX9
Accessions AAB93484 AAC24417 AAR29001 AAV28733 EAW73059 EAW73060 EAW73061 EAW73062 P48507 AB809606 BAN05309 AK290449 BAF83138 BC041809 AAH41809 BE269549 BE866085 BF031933 BF213407 BF219130 BF246042 BF513627 BF541340 BF541441 BF698337 BG291243 BG501583 BG547387 BI497338 BM468805 BM982562 BQ049850 BQ224592 BU600458 BU754400 C17598 C18245 C18878 C18959 C19097 CB114258 CB123306 CB128427 CK818048 CN272168 CN422503 CR541833 CAG46632 D63311 L35546 AAA65028 N53134 R69169 XM_005270754 XP_005270811 XM_011541261 XP_011539563 NM_001308253 NP_001295182 NM_002061 NP_002052
Tissue Specificity In all tissues examined. Highest levels in skeletal muscle.
Top Pathways Glutathione metabolism

γ-GCSm (E-4) - sc-55586 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
γ-GCSm (G-4): sc-55586. Western blot analysis of human recominant γ-GCSm fusion protein.

γ-GCSm (F-8) - sc-166603 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
γ-GCSm (F-8): sc-166603. Western blot analysis of γ-GCSm expression in K-562 (A), A549 (B) and c4 (C) whole cell lysates and rat liver (D) and mouse liver (E) tissue extracts.

γ-GCSm (FL-274) - sc-22754 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
γ-GCSm (FL-274): sc-22754. Immunoperoxidase staining of formalin fixed, paraffin-embedded human duodenum tissue showing cytoplasmic staining of glandular cells at low (A) and high (B) magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.

γ-GCSm (T-16) - sc-22663 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
γ-GCSm (T-16): sc-22663. Immunofluorescence staining of methanol-fixed A549 cells showing cytoplasmic localization.

γ-GCSm (G-4) - sc-55585 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
γ-GCSm (G-4): sc-55585. Western blot analysis of human recombinant γ-GCSm fusion protein.

Anti-GCLM antibody - ab55436 from Abcam

Prices $378.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
GCLM (ab55436) at 1ug/lane + HeLa cell lysate at 25ug/lane.

Anti-GCLM antibody - ab134760 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-GCLM antibody (ab134760) at 1/500 dilution + COS7 cell extract at 30 µg

Anti-GCLM antibody [AT2D12] - ab156613 from Abcam

Prices $376.00
Sizes 50 µl
Host Mouse
Clonality Monoclonal
Clone AT2D12
Anti-GCLM antibody [AT2D12] (ab156613) at 1/3000 dilution + HeLa cell lysate at 40 µgSecondaryGoat anti-mouse HRPdeveloped using the ECL technique

Anti-GCLM antibody [EPR6667] - ab126704 from Abcam

Prices $387.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR6667
Overlay histogram showing HeLa cells stained with ab126704 (red line). The cells were fixed with 80% methanol (5 min) and then permeabilized with 0.1% PBS-Tween for 20 min. The cells were then incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions followed by the antibody (ab126704, 1/100 dilution) for 30 min at 22°C. The secondary antibody used was Alexa Fluor® 488 goat anti-rabbit IgG (H+L) (ab150077) at 1/2000 dilution for 30 min at 22°C. Isotype control antibody (black line) was rabbit IgG (monoclonal) (1μg/1x106 cells) used under the same conditions. Unlabelled sample (blue line) was also used as a control. Acquisition of >5,000 events were collected using a 20mW Argon ion laser (488nm) and 525/30 bandpass filter.

Anti-GCLM antibody [EPR6668] - ab124827 from Abcam

Prices $385.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR6668
All lanes : Anti-GCLM antibody [EPR6668] (ab124827) at 1/1000 dilutionLane 1 : HeLa cell lysateLane 2 : A673 cell lysateLane 3 : K562 cell lysateLysates/proteins at 10 µg per lane.SecondaryHRP conjugated goat anti-rabbit at 1/2000 dilution

Anti-GCLM Antibody (aa246-274) - LS-C166413 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
GCLM Antibody IHC of formalin-fixed and paraffin-embedded skeletal muscle followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-GCLM Antibody - LS-C333974 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry of paraffin-embedded rat lung using GCLM antibody at dilution of 1:200 (400x lens).

Anti-GCLM Antibody (aa1-275, clone 10C341, Azide-free) - LS-C183645 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone 10C341

Anti-GCLM Antibody (aa246-274, AP) - LS-C214658 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GCLM Antibody (aa246-274, APC) - LS-C214660 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GCLM Antibody (aa246-274, Biotin) - LS-C214662 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GCLM Antibody (aa246-274, FITC) - LS-C214663 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GCLM Antibody (aa246-274, PE) - LS-C214664 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GCLM Antibody (aa246-274, Azide-free, HRP) - LS-C214665 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GCLM Antibody (clone AT2D12) - LS-C175814 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone AT2D12
Western Blot: The cell lysates of HeLa (40 ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human GCLM antibody (1:3000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.

Anti-GCLM Antibody (aa42-91) - LS-C286269 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-GCLM Antibody (Internal, clone EPR6667) - LS-C152336 from LifeSpan Bioscience

Prices $485.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR6667
IHC of paraffin-embedded human breast carcinoma tissue using anti-GCLM antibody.

Anti-GCLM Antibody - LS-C307658 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-GCLM Antibody - LS-C311169 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-GCLM Antibody - LS-C311168 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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