| Gene Symbol |
ESYT3
|
| Entrez Gene |
83850
|
| Alt Symbol |
CHR3SYT, E-Syt3, FAM62C
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
extended synaptotagmin-like protein 3
|
| Other Description |
chr3 synaptotagmin|extended synaptotagmin-3|family with sequence similarity 62 (C2 domain containing), member C
|
| Swissprots |
A8K0G5 Q8NDZ5 A0FGR9 Q6ZV21 Q9BQR9
|
| Accessions |
A0FGR9 AJ303366 CAC33888 AJ697972 AK125080 AK289530 BAF82219 AW513592 AW792835 BC037292 AAH37292 BQ435892 DA726011 DQ993202 ABJ97707 XM_006713776 XP_006713839 XM_006713777 XP_006713840 XM_011513220 XP_011511522 XM_011513221 XP_011511523 XR_427381 NM_031913 NP_114119
|
| Function |
Binds glycerophospholipids in a barrel-like domain and may play a role in cellular lipid transport (By similarity). Tethers the endoplasmic reticulum to the cell membrane and promotes the formation of appositions between the endoplasmic reticulum and the cell membrane. {ECO:0000250, ECO:0000269|PubMed:23791178}.
|
| Subcellular Location |
Cell membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Detected at sites of contact between the endoplasmic reticulum membrane and the cell membrane. Recruited to the cell membrane via the third C2 domain.
|
| Tissue Specificity |
Widely expressed with high level in cerebellum and skin. {ECO:0000269|PubMed:17360437}.
|
![Western Blot: ESYT3 Overexpression Lysate (Adult Normal) [NBP2-06103] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for ESYT3.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/6362_ESYT3%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-06103-img0001.jpg)