Gene Symbol | ESYT3 |
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Entrez Gene | 83850 |
Alt Symbol | CHR3SYT, E-Syt3, FAM62C |
Species | Human |
Gene Type | protein-coding |
Description | extended synaptotagmin-like protein 3 |
Other Description | chr3 synaptotagmin|extended synaptotagmin-3|family with sequence similarity 62 (C2 domain containing), member C |
Swissprots | A8K0G5 Q8NDZ5 A0FGR9 Q6ZV21 Q9BQR9 |
Accessions | A0FGR9 AJ303366 CAC33888 AJ697972 AK125080 AK289530 BAF82219 AW513592 AW792835 BC037292 AAH37292 BQ435892 DA726011 DQ993202 ABJ97707 XM_006713776 XP_006713839 XM_006713777 XP_006713840 XM_011513220 XP_011511522 XM_011513221 XP_011511523 XR_427381 NM_031913 NP_114119 |
Function | Binds glycerophospholipids in a barrel-like domain and may play a role in cellular lipid transport (By similarity). Tethers the endoplasmic reticulum to the cell membrane and promotes the formation of appositions between the endoplasmic reticulum and the cell membrane. {ECO:0000250, ECO:0000269|PubMed:23791178}. |
Subcellular Location | Cell membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Detected at sites of contact between the endoplasmic reticulum membrane and the cell membrane. Recruited to the cell membrane via the third C2 domain. |
Tissue Specificity | Widely expressed with high level in cerebellum and skin. {ECO:0000269|PubMed:17360437}. |
FAM62C CRISPR/Cas9 KO Plasmid (h) - sc-413509 from Santa Cruz Biotechnology
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FAM62C HDR Plasmid (h) - sc-413509-HDR from Santa Cruz Biotechnology
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FAM62C Double Nickase Plasmid (h) - sc-413509-NIC from Santa Cruz Biotechnology
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FAM62C Double Nickase Plasmid (h2) - sc-413509-NIC-2 from Santa Cruz Biotechnology
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FAM62C CRISPR Activation Plasmid (h) - sc-413509-ACT from Santa Cruz Biotechnology
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FAM62C CRISPR Activation Plasmid (h2) - sc-413509-ACT-2 from Santa Cruz Biotechnology
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FAM62C Lentiviral Activation Particles (h) - sc-413509-LAC from Santa Cruz Biotechnology
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FAM62C Lentiviral Activation Particles (h2) - sc-413509-LAC-2 from Santa Cruz Biotechnology
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FAM62C siRNA (h) - sc-78406 from Santa Cruz Biotechnology
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FAM62C shRNA Plasmid (h) - sc-78406-SH from Santa Cruz Biotechnology
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FAM62C shRNA (h) Lentiviral Particles - sc-78406-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU043051 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7998 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7998 from Sigma-Aldrich
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ESYT3 siRNA (Human) - CRJ3200 from Cohesion Biosciences
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ESYT3 - MBS828257 from MyBioSource
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shRNA set against Human ESYT3 (NM_031913.3) - SHH287513 from Creative biogene
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Human ESYT3 siRNA - orb273701 from Biorbyt
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ESYT3 shRNA Plasmid (Human) - CHJ3200 from Cohesion Biosciences
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ESYT3 miRNA 3'UTR clone - MiUTR3H-14766 from Creative biogene
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