DUT

Gene Symbol	DUT
Entrez Gene	1854
Alt Symbol	dUTPase
Species	Human
Gene Type	protein-coding
Description	deoxyuridine triphosphatase
Other Description	dUTP diphosphatase|dUTP nucleotidohydrolase|dUTP pyrophosphatase|deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial
Swissprots	Q6NSA3 Q16860 Q16708 Q6FHN1 A8K650 P33316 B4DPR5 O14785 Q96Q81
Accessions	AAB71393 AAB71394 AAB93866 AAB93867 AAX14045 EAW77349 EAW77350 EAW77351 EAW77352 P33316 AB049113 BAB13724 AK000629 AK291515 BAF84204 AK298464 BAG60677 AK312122 BAG35058 BC033645 AAH33645 BC070339 AAH70339 BC110377 AAI10378 BF697257 BG505144 BG532018 BI257870 CR541720 CAG46521 CR541781 CAG46580 DQ891191 ABM82117 DQ894375 ABM85301 L11877 AAA36801 M89913 AAA58444 U31930 AAC50418 U62891 AAC51123 U90223 AAB94642 XM_011521315 XP_011519617 XR_931760 NM_001025248 NP_001020419 NM_001025249 NP_001020420 NM_001948 NP_001939
Function	This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. {ECO:0000269|PubMed:8805593}.
Subcellular Location	Isoform 2: Nucleus.
Tissue Specificity	Found in a variety of tissues. Isoform 3 expression is constitutive, while isoform 2 expression correlates with the onset of DNA replication (at protein level). Isoform 2 degradation coincides with the cessation of nuclear DNA replication (at protein level). {ECO:0000269|PubMed:9228092}.
Top Pathways	Pyrimidine metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human DUT / DUTPase ELISA Kit (Sandwich ELISA) - LS-F11334 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.156 Range 0.156-10 ng/ml

Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial, DUT, Human, ELISA Kit - E1549h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 0.156-10 ng/mL

DUT (Human) Matched Antibody Pair - H00001854-AP51 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

Rat DUT / DUTPase ELISA Kit (Custom ELISA) - LS-F17974 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range 0.156-10 ng/ml

Human Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial ELISA Kit - abx251116 from Abbexa Category ELISA Kit Range 0.156 ng/ml - 10 ng/ml

Human Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial ELISA Kit - EKE53966 from Biomatik Category ELISA Kit Prices $685.40, $2,912.95, $5,483.20 Sizes 96 t, 5x96t, 10x96t Sensitivity The minimum detectable dose of this kit is typically less than 0.089 ng/mL Range 0.156-10 ng/mL

DUT - EKH3614 from Nordic BioSite Sensitivity 0.094ng/ml Range 0.156-10ng/ml

DUT ELISA Kit (Human) : 96 Wells (OKEH01114) - OKEH01114 from Aviva Systems Biology Category ELISA Kit Prices $420.00 Sizes 96 wells Sensitivity < 0.089 ng/mL Range 0.156 - 10 ng/mL

Human DUT ELISA Kit - E011713 from Biobool Category ELISA Kit Sensitivity <0.094ng/ml

Human Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial ELISA Kit - EK3779 from Signalway Antibody Category ELISA Kit Prices $599.00 Sizes 1x96t Sensitivity less than 0.1ng/mL Range 0.312-20 ng/mL

Deoxyuridine 5'-triphosphate nucleotidohydrolase, ELISA Kit - MBS2884676 from MyBioSource Category ELISA Kit Prices $380.00, $500.00, $2,170.00, $3,840.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Range 0.156-10 ng/mL

Deoxyuridine 5'-triphosphate nucleotidohydrolase, ELISA Kit - MBS9427609 from MyBioSource Category ELISA Kit Prices $555.00 Sizes 96 tests Sensitivity Less than 0.089ng/mL Range 0.156-10 ng/mL

Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial, ELISA Kit - MBS762984 from MyBioSource Category ELISA Kit Prices $295.00, $390.00, $1,615.00, $3,015.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.094ng/ml Range 0.156-10ng/ml

Human DUT / DUTPase ELISA Kit (Sandwich ELISA) - LS-F32900 from LifeSpan Bioscience Category ELISA Kit Sensitivity 0.094 Range 0.156-10 ng/ml

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