| Gene Symbol |
DPYSL3
|
| Entrez Gene |
1809
|
| Alt Symbol |
CRMP-4, CRMP4, DRP-3, DRP3, LCRMP, ULIP, ULIP-1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
dihydropyrimidinase-like 3
|
| Other Description |
collapsin response mediator protein 4 long|dihydropyrimidinase-related protein 3|unc-33-like phosphoprotein 1
|
| Swissprots |
Q93012 B3SXQ8 Q14195
|
| Accessions |
AAF76324 CAR95652 CAT03391 EAW61826 Q14195 AI570709 AK297223 BAG59706 BC039006 AAH39006 BC077077 AAH77077 CA424493 D78014 BAA11192 EU007906 ABV80252 EU832163 ACE87513 EU832180 ACE87530 EU832257 ACE86827 EU832273 ACE86843 Y07818 CAA69153 XM_011537574 XP_011535876 XM_011537575 XP_011535877 NM_001197294 NP_001184223 NM_001387 NP_001378
|
| Function |
Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cytoplasm {ECO:0000250}. Cell projection, growth cone {ECO:0000250}. Note=Colocalizes with synaptic vesicle protein 2 in the central region of the growth cone. {ECO:0000250}.
|
| Tissue Specificity |
Mainly expressed in heart and skeletal muscle. Also strongly expressed in fetal brain and spinal cord.
|
![Western Blot: CRMP4 Overexpression Lysate (Adult Normal) [NBL1-10009] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for CRMP4.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/3527_CRMP4%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-10009-img0002.jpg)