Gene Symbol | DPYSL3 |
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Entrez Gene | 1809 |
Alt Symbol | CRMP-4, CRMP4, DRP-3, DRP3, LCRMP, ULIP, ULIP-1 |
Species | Human |
Gene Type | protein-coding |
Description | dihydropyrimidinase-like 3 |
Other Description | collapsin response mediator protein 4 long|dihydropyrimidinase-related protein 3|unc-33-like phosphoprotein 1 |
Swissprots | Q93012 B3SXQ8 Q14195 |
Accessions | AAF76324 CAR95652 CAT03391 EAW61826 Q14195 AI570709 AK297223 BAG59706 BC039006 AAH39006 BC077077 AAH77077 CA424493 D78014 BAA11192 EU007906 ABV80252 EU832163 ACE87513 EU832180 ACE87530 EU832257 ACE86827 EU832273 ACE86843 Y07818 CAA69153 XM_011537574 XP_011535876 XM_011537575 XP_011535877 NM_001197294 NP_001184223 NM_001387 NP_001378 |
Function | Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000250}. Cell projection, growth cone {ECO:0000250}. Note=Colocalizes with synaptic vesicle protein 2 in the central region of the growth cone. {ECO:0000250}. |
Tissue Specificity | Mainly expressed in heart and skeletal muscle. Also strongly expressed in fetal brain and spinal cord. |
CRMP-4 CRISPR/Cas9 KO Plasmid (h) - sc-403305 from Santa Cruz Biotechnology
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CRMP-4 HDR Plasmid (h) - sc-403305-HDR from Santa Cruz Biotechnology
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CRMP-4 Double Nickase Plasmid (h) - sc-403305-NIC from Santa Cruz Biotechnology
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CRMP-4 Double Nickase Plasmid (h2) - sc-403305-NIC-2 from Santa Cruz Biotechnology
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CRMP-4 CRISPR Activation Plasmid (h) - sc-403305-ACT from Santa Cruz Biotechnology
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CRMP-4 CRISPR Activation Plasmid (h2) - sc-403305-ACT-2 from Santa Cruz Biotechnology
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CRMP-4 Lentiviral Activation Particles (h) - sc-403305-LAC from Santa Cruz Biotechnology
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CRMP-4 Lentiviral Activation Particles (h2) - sc-403305-LAC-2 from Santa Cruz Biotechnology
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CRMP-4 siRNA (h) - sc-44487 from Santa Cruz Biotechnology
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CRMP-4 shRNA Plasmid (h) - sc-44487-SH from Santa Cruz Biotechnology
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CRMP-4 shRNA (h) Lentiviral Particles - sc-44487-V from Santa Cruz Biotechnology
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CRMP4 RNAi - H00001809-R01 from Novus Biologicals
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MISSION® esiRNA - EHU040071 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7481 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7481 from Sigma-Aldrich
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DPYSL3 siRNA (Human) - CRH1261 from Cohesion Biosciences
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DPYSL3 - MBS8205319 from MyBioSource
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shRNA set against Human DPYSL3 (NM_001387.2) - SHH280897 from Creative biogene
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shRNA set against Human DPYSL3(NM_001387.2) - SHH015293 from Creative biogene
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Human DPYSL3 siRNA - orb261763 from Biorbyt
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DPYSL3 shRNA Plasmid (Human) - CHH1261 from Cohesion Biosciences
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DPYSL3 miRNA 3'UTR clone - MiUTR1H-02988 from Creative biogene
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