Aadat

Gene Symbol Aadat
Entrez Gene 23923
Alt Symbol AI875679, Aadt, KATII, Kat2, mKat-2
Species Mouse
Gene Type protein-coding
Description aminoadipate aminotransferase
Other Description 2-aminoadipate aminotransferase|2-aminoadipate transaminase|KAT/AadAT|alpha-aminoadipate aminotransferase|kynurenine aminotransferase II|kynurenine--oxoglutarate aminotransferase II|kynurenine--oxoglutarate transaminase 2|kynurenine--oxoglutarate transaminase II|kynurenine/alpha-aminoadipate aminotransferase, mitochondrial
Swissprots Q9WVM8
Accessions EDL28634 Q9WVM8 AF072376 AAD39680 AK075578 BAC35833 AK144042 BAE25669 BC012637 AAH12637 XM_006509397 XP_006509460 XM_011242215 XP_011240517 NM_011834 NP_035964
Function Transaminase with broad substrate specificity. Has transaminase activity towards aminoadipate, kynurenine, methionine and glutamate. Shows activity also towards tryptophan, aspartate and hydroxykynurenine. Accepts a variety of oxo-acids as amino- group acceptors, with a preference for 2-oxoglutarate, 2- oxocaproic acid, phenylpyruvate and alpha-oxo-gamma-methiol butyric acid. Can also use glyoxylate as amino-group acceptor (in vitro) (By similarity). {ECO:0000250}.
Subcellular Location Mitochondrion {ECO:0000305}.
Tissue Specificity Expressed mainly in kidney and to a lesser amount in liver and brain. {ECO:0000269|PubMed:10441733}.
Top Pathways Lysine degradation, Tryptophan metabolism, Lysine biosynthesis, Biosynthesis of amino acids, 2-Oxocarboxylic acid metabolism

KAT II CRISPR/Cas9 KO Plasmid (m) - sc-423898 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

KAT II HDR Plasmid (m) - sc-423898-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

KAT II Double Nickase Plasmid (m) - sc-423898-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

KAT II Double Nickase Plasmid (m2) - sc-423898-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

KAT II CRISPR Activation Plasmid (m) - sc-423898-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

KAT II CRISPR Activation Plasmid (m2) - sc-423898-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

KAT II Lentiviral Activation Particles (m) - sc-423898-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

KAT II Lentiviral Activation Particles (m2) - sc-423898-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Mouse

KAT II siRNA (m) - sc-77359 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

KAT II shRNA Plasmid (m) - sc-77359-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

KAT II shRNA (m) Lentiviral Particles - sc-77359-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Mouse

CompoZr® Knockout ZFN Kit - CKOZFN26002 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND26002 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

AADAT siRNA (Mouse) - CRM4582 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

AADAT - MBS8221814 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

shRNA set against Mouse AADAT (NM_011834.2) - SHH228582 from Creative biogene

Category siRNA
Species Reactivities Mouse

shRNA set against Mouse Aadat(NM_011834.2) - SHG021965 from Creative biogene

Category siRNA
Species Reactivities Mouse

Mouse AADAT siRNA - orb284058 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Mouse

AADAT shRNA Plasmid (Mouse) - CHM4582 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Mouse

AADAT miRNA 3'UTR clone - MiUTR1M-01007 from Creative biogene

Species Reactivities Mouse
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