| Gene Symbol |
AP1G2
|
| Entrez Gene |
8906
|
| Alt Symbol |
G2AD
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
adaptor-related protein complex 1, gamma 2 subunit
|
| Other Description |
AP-1 complex subunit gamma-like 2|clathrin-associated/assembly/adaptor protein, large, gamma-2|gamma2-adaptin
|
| Swissprots |
D3DS51 O75843 O75504
|
| Accessions |
CCQ43243 EAW66132 EAW66134 EAW66138 O75843 AB015318 BAA33390 AF068706 AAC67390 AI497879 AK096034 AK123354 AK226158 AK304682 BAG65453 AK307696 AK309103 AK310451 AW451370 BC051833 AAH51833 BG701521 BI918958 BQ073124 BX161425 CAD61898 BX247963 CAD62302 H41406 XM_005268167 XP_005268224 XM_005268168 XP_005268225 XM_005268169 XP_005268226 XM_005268170 XP_005268227 XM_005268172 XP_005268229 XM_005268173 XP_005268230 XM_005268174 XP_005268231 XM_005268175 XP_005268232 XM_005268177 XP_005268234 XM_005268178 XP_005268235 XM_005268179 XP_005268236 XM_005268180 XP_005268237 XM_005268181 XP_005268238 XM_005268182 XP_005268239 XM_006720301 XP_006720364 XM_011537282 XP_011535584 XM_011537283 XP_011535585 XM_011537284 XP_011535586 XM_011537285 XP_011535587 XM_011537286 XP_011535588 XR_943550 XR_943551 XR_943552 XR_943553 XR_943554 XR_943555 NM_001282474 NP_001269403 NM_001282475 NP_001269404 NM_003917 NP_003908 NM_080545
|
| Function |
May function in protein sorting in late endosomes or multivesucular bodies (MVBs). Involved in MVB-assisted maturation of hepatitis B virus (HBV). {ECO:0000269|PubMed:16867982, ECO:0000269|PubMed:17553870, ECO:0000269|PubMed:9733768}.
|
| Subcellular Location |
Golgi apparatus membrane; Peripheral membrane protein. Cytoplasmic vesicle membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein. Note=Mainly localized to perinuclear vesicular structures. Colocalizes with HBV major surface antigen L and HBV core protein C in CD63-containing compartments. Colocalizes with HBV major surface antigen L to cis-Golgi-like structures.
|
| Tissue Specificity |
Expressed in all but one (skeletal muscle) tissues examined.
|
| Top Pathways |
Lysosome
|