| Gene Symbol |
TLE6
|
| Entrez Gene |
79816
|
| Alt Symbol |
GRG6
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
transducin-like enhancer of split 6
|
| Other Description |
transducin-like enhancer of split 6 (E(sp1) homolog, Drosophila)|transducin-like enhancer protein 6
|
| Swissprots |
Q9H808 J3KMZ1
|
| Accessions |
AAD38076 EAW69350 EAW69351 EAW69352 EAW69353 Q9H808 AK024071 BAB14815 AK308771 BC007215 AAH07215 BC007329 BC013986 AAH13986 BC020206 AAH20206 BC068052 BX089956 DA013757 DB059462 XM_005259645 XP_005259702 XM_011528300 XP_011526602 XM_011528301 XP_011526603 XM_011528302 XP_011526604 XM_011528303 XP_011526605 XM_011528304 XP_011526606 XM_011528305 XP_011526607 XM_011528306 XP_011526608 XM_011528307 XP_011526609 NM_001143986 NP_001137458 NM_024760 NP_079036
|
| Function |
As a member of the subcortical maternal complex (SCMC), plays an essential role for zygotes to progress beyond the first embryonic cell divisions. {ECO:0000250}.
|
| Subcellular Location |
Cytoplasm. Note=In the subcortical cytoplasm of early embryos from the 1-cell to the blastocyst stages. From the 2-cell stage, still detected in the subcortex, but excluded from cell-cell contact regions (By similarity). {ECO:0000250}.
|
![Western Blot: TLE6 Overexpression Lysate (Adult Normal) [NBL1-16946] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for TLE6.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/7197_TLE6%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-16946-img0002.jpg)