Gene Symbol | TLE6 |
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Entrez Gene | 79816 |
Alt Symbol | GRG6 |
Species | Human |
Gene Type | protein-coding |
Description | transducin-like enhancer of split 6 |
Other Description | transducin-like enhancer of split 6 (E(sp1) homolog, Drosophila)|transducin-like enhancer protein 6 |
Swissprots | Q9H808 J3KMZ1 |
Accessions | AAD38076 EAW69350 EAW69351 EAW69352 EAW69353 Q9H808 AK024071 BAB14815 AK308771 BC007215 AAH07215 BC007329 BC013986 AAH13986 BC020206 AAH20206 BC068052 BX089956 DA013757 DB059462 XM_005259645 XP_005259702 XM_011528300 XP_011526602 XM_011528301 XP_011526603 XM_011528302 XP_011526604 XM_011528303 XP_011526605 XM_011528304 XP_011526606 XM_011528305 XP_011526607 XM_011528306 XP_011526608 XM_011528307 XP_011526609 NM_001143986 NP_001137458 NM_024760 NP_079036 |
Function | As a member of the subcortical maternal complex (SCMC), plays an essential role for zygotes to progress beyond the first embryonic cell divisions. {ECO:0000250}. |
Subcellular Location | Cytoplasm. Note=In the subcortical cytoplasm of early embryos from the 1-cell to the blastocyst stages. From the 2-cell stage, still detected in the subcortex, but excluded from cell-cell contact regions (By similarity). {ECO:0000250}. |
TLE6 CRISPR/Cas9 KO Plasmid (h) - sc-413253 from Santa Cruz Biotechnology
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TLE6 HDR Plasmid (h) - sc-413253-HDR from Santa Cruz Biotechnology
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TLE6 Double Nickase Plasmid (h) - sc-413253-NIC from Santa Cruz Biotechnology
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TLE6 Double Nickase Plasmid (h2) - sc-413253-NIC-2 from Santa Cruz Biotechnology
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TLE6 CRISPR Activation Plasmid (h) - sc-413253-ACT from Santa Cruz Biotechnology
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TLE6 CRISPR Activation Plasmid (h2) - sc-413253-ACT-2 from Santa Cruz Biotechnology
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TLE6 Lentiviral Activation Particles (h) - sc-413253-LAC from Santa Cruz Biotechnology
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TLE6 Lentiviral Activation Particles (h2) - sc-413253-LAC-2 from Santa Cruz Biotechnology
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TLE6 siRNA (h) - sc-97764 from Santa Cruz Biotechnology
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TLE6 shRNA Plasmid (h) - sc-97764-SH from Santa Cruz Biotechnology
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TLE6 shRNA (h) Lentiviral Particles - sc-97764-V from Santa Cruz Biotechnology
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TLE6 RNAi - H00079816-R01 from Novus Biologicals
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MISSION® esiRNA - EHU140391 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN21393 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21393 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR00700 from Sigma-Aldrich
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TLE6 siRNA (Human) - CRJ2586 from Cohesion Biosciences
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TLE6 - MBS8220877 from MyBioSource
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shRNA set against Human TLE6 (NM_024760.2) - SHH427840 from Creative biogene
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Human TLE6 siRNA - orb273087 from Biorbyt
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TLE6 shRNA Plasmid (Human) - CHJ2586 from Cohesion Biosciences
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TLE6 miRNA 3'UTR clone - MiUTR4H-TG09000 from Creative biogene
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