Gene Symbol | MT3 |
---|---|
Entrez Gene | 4504 |
Alt Symbol | GIF, GIFB, GRIF, ZnMT3 |
Species | Human |
Gene Type | protein-coding |
Description | metallothionein 3 |
Other Description | MT-3|MT-III|growth inhibitory factor|metallothionein 3 (growth inhibitory factor (neurotrophic))|metallothionein-3|metallothionein-III |
Swissprots | Q2V574 P25713 |
Accessions | AAA36214 AAB31396 ABB84467 EAW82866 EAW82867 EAW82868 P25713 BC013081 AAH13081 BC035624 BC047694 BI752092 BI820409 BT007030 AAP35677 CB155600 D13365 DQ891752 ABM82678 DQ894933 ABM85859 X89604 CAA61763 NM_005954 NP_005945 |
Function | Binds heavy metals. Contains three zinc and three copper atoms per polypeptide chain and only a negligible amount of cadmium. Inhibits survival and neurite formation of cortical neurons in vitro. |
Tissue Specificity | Abundant in a subset of astrocytes in the normal human brain, but greatly reduced in the Alzheimer disease (AD) brain. |
Metallothionein 3 CRISPR/Cas9 KO Plasmid (h) - sc-403201 from Santa Cruz Biotechnology
|
||||||||
Metallothionein 3 HDR Plasmid (h) - sc-403201-HDR from Santa Cruz Biotechnology
|
||||||||
Metallothionein 3 Double Nickase Plasmid (h) - sc-403201-NIC from Santa Cruz Biotechnology
|
||||||||
Metallothionein 3 Double Nickase Plasmid (h2) - sc-403201-NIC-2 from Santa Cruz Biotechnology
|
||||||||
Metallothionein 3 CRISPR Activation Plasmid (h) - sc-403201-ACT from Santa Cruz Biotechnology
|
||||||||
Metallothionein 3 CRISPR Activation Plasmid (h2) - sc-403201-ACT-2 from Santa Cruz Biotechnology
|
||||||||
Metallothionein 3 Lentiviral Activation Particles (h) - sc-403201-LAC from Santa Cruz Biotechnology
|
||||||||
Metallothionein 3 Lentiviral Activation Particles (h2) - sc-403201-LAC-2 from Santa Cruz Biotechnology
|
||||||||
Metallothionein 3 siRNA (h) - sc-93438 from Santa Cruz Biotechnology
|
||||||||
Metallothionein 3 shRNA Plasmid (h) - sc-93438-SH from Santa Cruz Biotechnology
|
||||||||
Metallothionein 3 shRNA (h) Lentiviral Particles - sc-93438-V from Santa Cruz Biotechnology
|
||||||||
GIF RNAi - H00002694-R01 from Novus Biologicals
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN14682 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14682 from Sigma-Aldrich
|
||||||||
MISSION® 3′UTR Lenti GoClone™ - HUTR00102 from Sigma-Aldrich
|
||||||||
MT3 siRNA (Human) - CRH2990 from Cohesion Biosciences
|
||||||||
shRNA set against Human MT3 (NM_005954.2) - SHH346028 from Creative biogene
|
||||||||
MT3 shRNA Plasmid (Human) - CHH2990 from Cohesion Biosciences
|
||||||||
MT3 miRNA 3'UTR clone - MiUTR1H-06495 from Creative biogene
|