| Gene Symbol |
NDUFB8
|
| Entrez Gene |
4714
|
| Alt Symbol |
ASHI, CI-ASHI
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa
|
| Other Description |
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial|NADH-ubiquinone oxidoreductase ASHI subunit|NADH:ubiquinone oxidoreductase ASHI subunit|complex I ASHI subunit|complex I-ASHI
|
| Swissprots |
Q5W145 Q5W144 A8K0L4 Q9UQF3 Q9UJR4 O95169 Q5W143 Q9UG53
|
| Accessions |
CAB46274 EAW49819 EAW49820 O95169 AA782554 AF044958 AAD05422 AF077028 AAD27761 AF115968 AAP97239 AI282606 AK289579 BAF82268 AL080056 CAB45691 BC000466 AAH00466 BC019276 AAH19276 BM008944 BM686677 CF127298 CR533490 CAG38521 DA428446 DQ893286 ABM84212 DQ896618 ABM87617 EU831639 ACE87239 EU831723 ACE86557 NM_001284367 NP_001271296 NM_001284368 NP_001271297 NM_005004 NP_004995
|
| Function |
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
|
| Subcellular Location |
Mitochondrion inner membrane; Single-pass membrane protein; Matrix side.
|
| Top Pathways |
Alzheimer's disease, Huntington's disease, Non-alcoholic fatty liver disease (NAFLD), Oxidative phosphorylation
|
![Western Blot: NDUFB8 Overexpression Lysate (Adult Normal) [NBL1-13556] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for NDUFB8.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/10616_NDUFB8%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-13556-img0002.jpg)