Gene Symbol | NDUFB8 |
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Entrez Gene | 4714 |
Alt Symbol | ASHI, CI-ASHI |
Species | Human |
Gene Type | protein-coding |
Description | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa |
Other Description | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial|NADH-ubiquinone oxidoreductase ASHI subunit|NADH:ubiquinone oxidoreductase ASHI subunit|complex I ASHI subunit|complex I-ASHI |
Swissprots | Q5W145 Q5W144 A8K0L4 Q9UQF3 Q9UJR4 O95169 Q5W143 Q9UG53 |
Accessions | CAB46274 EAW49819 EAW49820 O95169 AA782554 AF044958 AAD05422 AF077028 AAD27761 AF115968 AAP97239 AI282606 AK289579 BAF82268 AL080056 CAB45691 BC000466 AAH00466 BC019276 AAH19276 BM008944 BM686677 CF127298 CR533490 CAG38521 DA428446 DQ893286 ABM84212 DQ896618 ABM87617 EU831639 ACE87239 EU831723 ACE86557 NM_001284367 NP_001271296 NM_001284368 NP_001271297 NM_005004 NP_004995 |
Function | Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. |
Subcellular Location | Mitochondrion inner membrane; Single-pass membrane protein; Matrix side. |
Top Pathways | Alzheimer's disease, Huntington's disease, Non-alcoholic fatty liver disease (NAFLD), Oxidative phosphorylation |
NDUFB8 CRISPR/Cas9 KO Plasmid (h) - sc-408010 from Santa Cruz Biotechnology
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NDUFB8 HDR Plasmid (h) - sc-408010-HDR from Santa Cruz Biotechnology
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NDUFB8 Double Nickase Plasmid (h) - sc-408010-NIC from Santa Cruz Biotechnology
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NDUFB8 Double Nickase Plasmid (h2) - sc-408010-NIC-2 from Santa Cruz Biotechnology
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NDUFB8 CRISPR Activation Plasmid (h) - sc-408010-ACT from Santa Cruz Biotechnology
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NDUFB8 CRISPR Activation Plasmid (h2) - sc-408010-ACT-2 from Santa Cruz Biotechnology
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NDUFB8 Lentiviral Activation Particles (h) - sc-408010-LAC from Santa Cruz Biotechnology
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NDUFB8 Lentiviral Activation Particles (h2) - sc-408010-LAC-2 from Santa Cruz Biotechnology
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NDUFB8 siRNA (h) - sc-90752 from Santa Cruz Biotechnology
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NDUFB8 shRNA Plasmid (h) - sc-90752-SH from Santa Cruz Biotechnology
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NDUFB8 shRNA (h) Lentiviral Particles - sc-90752-V from Santa Cruz Biotechnology
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NDUFB8 RNAi - H00004714-R01 from Novus Biologicals
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MISSION® esiRNA - EHU108191 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN15162 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15162 from Sigma-Aldrich
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NDUFB8 siRNA (Human) - CRH3128 from Cohesion Biosciences
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shRNA set against Human NDUFB8 (NM_005004.2) - SHH350792 from Creative biogene
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shRNA set against Human NDUFB8(NM_005004.2) - SHR005430 from Creative biogene
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NDUFB8 shRNA Plasmid (Human) - CHH3128 from Cohesion Biosciences
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NDUFB8 miRNA 3'UTR clone - MiUTR1H-06705 from Creative biogene
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