| Gene Symbol |
DNAJC6
|
| Entrez Gene |
9829
|
| Alt Symbol |
DJC6, PARK19
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
DnaJ (Hsp40) homolog, subfamily C, member 6
|
| Other Description |
DnaJ (Hsp40) homolog, subfamily B, member 6|auxilin|putative tyrosine-protein phosphatase auxilin
|
| Swissprots |
Q5T614 Q32M66 O75061 D3DQ65 B7Z3V8 D3DQ66 Q5T615 Q4G0K1
|
| Accessions |
CCE46052 EAX06533 EAX06534 EAX06535 EAX06536 EAX06537 O75061 AB007942 BAA32318 AK296408 BAH12344 BC051722 AAH51722 BC109279 AAI09280 BC109280 AAI09281 BP311649 BQ423527 BX647203 CR747692 DC332732 DR002818 XM_011542483 XP_011540785 XM_011542484 XP_011540786 XM_011542485 XP_011540787 XM_011542486 XP_011540788 XM_011542487 XP_011540789 XM_011542488 XP_011540790 XM_011542489 XP_011540791 NM_001256864 NP_001243793 NM_001256865 NP_001243794 NM_014787 NP_055602
|
| Function |
Recruits HSPA8/HSC70 to clathrin-coated vesicles and promotes uncoating of clathrin-coated vesicles. Plays a role in clathrin-mediated endocytosis in neurons (By similarity). {ECO:0000250}.
|
| Tissue Specificity |
Expressed in various brain regions, including cerebellum, corpus callosum, cortex, striatum, brainstem, pons, putamen, spinal cord and substantia nigra. Very low expression in non-neural tissues such as leukocytes, liver, adipose tissue, skeletal muscle and bone marrow. {ECO:0000269|PubMed:23211418}.
|
| Top Pathways |
Endocytosis
|
![Western Blot: DNAJC6 Overexpression Lysate (Adult Normal) [NBP2-07267] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for DNAJC6.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/18295_DNAJC6%2520Overexpression%2520Lysate%2520%2528Adult%2520Normal%2529-Western%2520Blot-NBP2-07267-img0001.jpg)