AGR2

Gene Symbol AGR2
Entrez Gene 10551
Alt Symbol AG2, GOB-4, HAG-2, HEL-S-116, PDIA17, XAG-2
Species Human
Gene Type protein-coding
Description anterior gradient 2
Other Description AG-2|HPC8|anterior gradient homolog 2|anterior gradient protein 2 homolog|epididymis secretory protein Li 116|protein disulfide isomerase family A, member 17|secreted cement gland homolog|secreted cement gland protein XAG-2 homolog
Swissprots O95994
Accessions AAP22354 AAY84773 AAY84774 AAY84775 AAY84776 CAC69703 CAM55980 EAL24283 EAW93682 EAW93683 O95994 AF007791 AAC77358 AF038451 AAC82614 AF038452 AF087879 AAP97179 AF088867 AAF22484 AF115926 AAL54870 AK223067 BAD96787 AK296721 BAG59310 AK312942 BAG35784 AY359009 AAQ89368 BC015503 AAH15503 BF680655 BT007048 AAP35697 DQ890645 ABM81571 DQ893825 ABM84751 FJ224307 ACI45999 KJ767789 AJO53280 KJ767791 KJ767792 KJ767793 XM_005249581 XP_005249638 NM_006408 NP_006399
Function Required for MUC2 post-transcriptional synthesis and secretion. May play a role in the production of mucus by intestinal cells (By similarity). Proto-oncogene that may play a role in cell migration, cell differentiation and cell growth. {ECO:0000250, ECO:0000269|PubMed:18199544}.
Subcellular Location Secreted {ECO:0000269|PubMed:15834940}. Endoplasmic reticulum {ECO:0000250}.
Tissue Specificity Expressed strongly in trachea, lung, stomach, colon, prostate and small intestine. Expressed weakly in pituitary gland, salivary gland, mammary gland, bladder, appendix, ovary, fetal lung, uterus, pancreas, kidney, fetal kidney, testis, placenta, thyroid gland and in estrogen receptor (ER)-positive breast cancer cell lines. {ECO:0000269|PubMed:9790916}.

AGR2 (D9V2F) XP ® Rabbit mAb - 13062 from Cell Signaling Technology

Prices $109.00, $282.00
Sizes 20 µl (2 western blots), 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D9V2F
Western blot analysis of extracts from various cell lines using AGR2 (D9V2F) XP ® Rabbit mAb (upper) and β-Actin (D6A8) Rabbit mAb #8457 (lower).

AGR2 Antibody - 8992 from Cell Signaling Technology

Host Rabbit
Clonality Polyclonal

AGR2 (D-18) - sc-54560 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

AGR2 (Y-14) - sc-54562 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
AGR2 (Y-14): sc-54562. Western blot analysis of AGR2 expression in MCF7 whole cell lysate.

AGR2 (6C5) - sc-101211 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
AGR2 (6C5): sc-101211. Western blot analysis of AGR2 expression in non-transfected 293: sc-110760 (A), human AGR2 transfected 293: sc-112951 (B) and MCF7 (C) whole cell lysates.

AGR2/3 (C-7) - sc-376653 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
AGR2/3 (C-7): sc-376653. Western blot analysis of AGR2/3 expression in MCF7 whole cell lysate.

AGR2/3 (H-47) - sc-135068 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-AGR2 + AGR3 antibody [AGR3.4] - ab82399 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone AGR3.4
All lanes : Anti-AGR2 + AGR3 antibody [AGR3.4] (ab82399) at 1 µg/mlLane 1 : H1299 lung carcinoma cell lineLane 2 : T47D breast cancer cell line

Anti-Anterior Gradient 2 antibody - ab56703 from Abcam

Prices $384.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-Anterior Gradient 2 antibody - ab181339 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of Paraffin-embedded Human small intestine tissue labeling Anterior Gradient 2 with ab181339 at 5 µg/ml.

Anti-Anterior Gradient 2 antibody [EPR3278] - ab76473 from Abcam

Prices $387.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR3278
All lanes : Anti-Anterior Gradient 2 antibody [EPR3278] (ab76473) at 1/10000 dilutionLane 1 : HT-29 cell lysatesLane 2 : MCF-7 cell lysatesLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-Anterior Gradient 2 antibody [EPR3278] (Alexa Fluor® 488) - ab199044 from Abcam

Prices $425.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR3278
ab199044 staining Anterior Gradient 2 in A549 cells. The cells were fixed with 100% methanol (5min), permeabilized with 0.1% Triton X-100 for 5 minutes and then blocked with 1% BSA/10% normal goat serum/0.3M glycine in 0.1% PBS-Tween for 1h. The cells were then incubated overnight at +4°C with ab199044 at 1/100 dilution (shown in green) and ab195889, Mouse monoclonal to alpha Tubulin (Alexa Fluor® 594), at 2 µg/ml (shown in red). Nuclear DNA was labelled with DAPI (shown in blue).Image was taken with a confocal microscope (Leica-Microsystems, TCS SP8).This product also gave a positive signal under the same testing conditions in A549 cells fixed with 4% formaldehyde (10 min).

Anti-Anterior Gradient 2 antibody [EPR3278] (Alexa Fluor® 647) - ab199246 from Abcam

Prices $425.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR3278
ab199246 staining Anterior Gradient 2 in A549 cells. The cells were fixed with 4% formaldehyde (10min), permeabilized with 0.1% Triton X-100 for 5 minutes and then blocked with 1% BSA/10% normal goat serum/0.3M glycine in 0.1% PBS-Tween for 1h. The cells were then incubated overnight at +4°C with ab199246 at 1/100 dilution (shown in red) and ab195887, Mouse monoclonal to alpha Tubulin (Alexa Fluor® 488), at 2 µg/ml (shown in green). Nuclear DNA was labelled with DAPI (shown in blue).Image was taken with a confocal microscope (Leica-Microsystems, TCS SP8).

Anti-Anterior Gradient 2 antibody [EPR3278] (DyLight® 488) - ab139894 from Abcam

Prices $337.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR3278
Immunofluorescent analysis of HeLa cells labelling Anterior Gradient 2 with ab139894 at 1/100 dilution (green); Dapi staining shown in blue.

Anti-Anterior Gradient 2 antibody [EPR3279] - ab134167 from Abcam

Host Rabbit
Clonality Monoclonal
Clone EPR3279
All lanes : Anti-Anterior Gradient 2 antibody [EPR3279] (ab134167) at 1/500 dilutionLane 1 : HT29 cell lysateLane 2 : MCF7 cell lysateLysates/proteins at 10 µg per lane.SecondaryStandard HRP labelled goat anti-rabbit at 1/2000 dilutiondeveloped using the ECL technique

Anti-AGR2 Antibody (aa21-175) - LS-C122675 from LifeSpan Bioscience

Prices $605.00
Sizes 100 µg
Host Sheep
Clonality Polyclonal

Anti-AGR2 Antibody (Internal, Biotin) - LS-C142491 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-AGR2 Antibody (Internal, DY488) - LS-C142493 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-AGR2 Antibody (Internal, DY650) - LS-C142492 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-AGR2 Antibody (Internal, HRP) - LS-C142494 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-AGR2 Antibody (Internal, DY550) - LS-C142495 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-AGR2 Antibody (N-Terminus, Biotin) - LS-C142497 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-AGR2 Antibody (N-Terminus, DY650) - LS-C142498 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-AGR2 Antibody (N-Terminus, HRP) - LS-C142500 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-AGR2 Antibody (N-Terminus, DY550) - LS-C142501 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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