Gene Symbol | HLA-DOB |
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Entrez Gene | 3112 |
Alt Symbol | DOB |
Species | Human |
Gene Type | protein-coding |
Description | major histocompatibility complex, class II, DO beta |
Other Description | HLA class II histocompatibility antigen, DO beta chain|MHC class II antigen DOB |
Swissprots | Q29746 Q6FHC2 Q29825 B0V0Y0 P13765 |
Accessions | AAA59717 AHW47923 AHW47940 AHW47957 AHW47974 CAA47028 CAA60789 EAX03638 EAX03639 EAX03640 EAX03641 P13765 AK301415 BAH13478 AK316197 BAH14568 AY645723 AAV97948 BC006097 AAH06097 BC020226 BM152694 BQ010608 CR541811 CAG46610 CR541832 CAG46631 M26040 AAA59718 X03066 CAA26870 NM_002120 NP_002111 |
Function | Important modulator in the HLA class II restricted antigen presentation pathway by interaction with the HLA-DM molecule in B-cells. Modifies peptide exchange activity of HLA-DM. |
Subcellular Location | Endosome membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Note=Complexes with HLA-DM molecule during intracellular transport and in endosomal/lysosomal compartments. Heterotetramerization is necessary to exit the ER. |
Top Pathways | Leishmaniasis, HTLV-I infection, Influenza A, Tuberculosis, Herpes simplex infection |
HLA-DOβ (DOB.L1) - sc-69739 from Santa Cruz Biotechnology
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HLA-DOβ (V-16) - sc-14543 from Santa Cruz Biotechnology
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Anti-HLA DOB antibody - ab103168 from Abcam
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Anti-HLA DOB antibody - ab136842 from Abcam
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Anti-HLA DOB antibody - ab67424 from Abcam
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Anti-HLA-DOB Antibody (aa1-50) - LS-C291337 from LifeSpan Bioscience
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Anti-HLA-DOB Antibody (aa33-82) - LS-C292055 from LifeSpan Bioscience
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Anti-HLA-DOB Antibody - LS-C308256 from LifeSpan Bioscience
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Anti-HLA-DOB Antibody - LS-C311220 from LifeSpan Bioscience
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Anti-HLA-DOB Antibody (aa43-88) - LS-C313792 from LifeSpan Bioscience
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Anti-HLA-DOB Antibody - LS-C311221 from LifeSpan Bioscience
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Anti-HLA-DOB Antibody (clone DOB 10E6/5, Biotin) - LS-C347846 from LifeSpan Bioscience
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Anti-HLA-DOB Antibody (clone DOB 10E6/5, FITC) - LS-C347847 from LifeSpan Bioscience
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Anti-HLA-DOB Antibody (N-Terminus) - LS-C187252 from LifeSpan Bioscience
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Anti-HLA-DOB Antibody (clone DOB 10E6/5) - LS-C348229 from LifeSpan Bioscience
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HLA DOB Antibody - H00003112-B01P from Novus Biologicals
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HLA DOB Antibody - H00003112-B01 from Novus Biologicals
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HLA DOB Antibody - H00003112-D01P from Novus Biologicals
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HLA DOB Antibody - NBP1-87469 from Novus Biologicals
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HLA DOB Antibody - H00003112-D01 from Novus Biologicals
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HLA DOB Antibody - H00003112-A01 from Novus Biologicals
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Anti-HLA-DOB antibody produced in rabbit - HPA013846 from Sigma-Aldrich
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Anti-HLA-DOB antibody produced in mouse - SAB1405940 from Sigma-Aldrich
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Anti-HLA-DOB antibody produced in rabbit - SAB1401176 from Sigma-Aldrich
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HLA-DOB Antibody - N-terminal region (ARP61712_P050) - ARP61712_P050 from Aviva Systems Biology
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