HLA-DOB

Gene Symbol	HLA-DOB
Entrez Gene	3112
Alt Symbol	DOB
Species	Human
Gene Type	protein-coding
Description	major histocompatibility complex, class II, DO beta
Other Description	HLA class II histocompatibility antigen, DO beta chain|MHC class II antigen DOB
Swissprots	Q29746 Q6FHC2 Q29825 B0V0Y0 P13765
Accessions	AAA59717 AHW47923 AHW47940 AHW47957 AHW47974 CAA47028 CAA60789 EAX03638 EAX03639 EAX03640 EAX03641 P13765 AK301415 BAH13478 AK316197 BAH14568 AY645723 AAV97948 BC006097 AAH06097 BC020226 BM152694 BQ010608 CR541811 CAG46610 CR541832 CAG46631 M26040 AAA59718 X03066 CAA26870 NM_002120 NP_002111
Function	Important modulator in the HLA class II restricted antigen presentation pathway by interaction with the HLA-DM molecule in B-cells. Modifies peptide exchange activity of HLA-DM.
Subcellular Location	Endosome membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Note=Complexes with HLA-DM molecule during intracellular transport and in endosomal/lysosomal compartments. Heterotetramerization is necessary to exit the ER.
Top Pathways	Leishmaniasis, HTLV-I infection, Influenza A, Tuberculosis, Herpes simplex infection

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

HLA-DOβ siRNA (h) - sc-42913 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

HLA-DOβ shRNA Plasmid (h)-SH - sc-42913-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

HLA-DOβ shRNA (h) Lentiviral Particles - sc-42913-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

HLA DOB RNAi - H00003112-R02 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU110801 from Sigma-Aldrich Category siRNA Prices $250.00 Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN10132 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10132 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR05070 from Sigma-Aldrich Category miRNA

HLA-DOB siRNA (Human) - CRH2125 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

HLA-DOB - MBS8235251 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human HLA-DOB(NM_002120.3) - SHR200194 from Creative biogene Category siRNA Species Reactivities Human

Human HLA-DOB siRNA - orb262627 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

HLA-DOB shRNA Plasmid (Human) - CHH2125 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

HLA-DOB miRNA 3'UTR clone - MiUTR1H-04581 from Creative biogene Species Reactivities Human

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