| Gene Symbol |
RHO
|
| Entrez Gene |
6010
|
| Alt Symbol |
CSNBAD1, OPN2, RP4
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
rhodopsin
|
| Other Description |
opsin 2, rod pigment|opsin-2
|
| Swissprots |
Q2M249 Q16414 P08100
|
| Accessions |
AAA97436 AAB35906 AAC31763 AAD14357 AIK20539 BAC05894 EAW79244 P08100 AM392780 CAL37658 BC111451 AAI11452 BC112104 AAI12105 BC112106 AAI12107 BX537381 CAD97623 NM_000539 NP_000530
|
| Function |
Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth. Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change leading to G-protein activation and release of all-trans retinal.
|
| Subcellular Location |
Membrane {ECO:0000269|PubMed:19934218}; Multi-pass membrane protein {ECO:0000269|PubMed:19934218}. Note=Synthesized in the inner segment (IS) of rod photoreceptor cells before vectorial transport to the rod outer segment (OS) photosensory cilia.
|
| Tissue Specificity |
Rod shaped photoreceptor cells which mediates vision in dim light.
|
| Top Pathways |
Phototransduction
|