Gene Symbol |
TAS2R39
|
Entrez Gene |
259285
|
Alt Symbol |
T2R39, T2R57
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
taste receptor, type 2, member 39
|
Other Description |
taste receptor type 2 member 39|taste receptor type 2 member 57
|
Swissprots |
Q3ZCN6 P59534 Q645W4 A4FUI7
|
Accessions |
AAM19321 BAD98035 BAD98036 BAD98037 CAI53576 EAW51884 EAW51885 EAW51886 P59534 BC100947 AAI00948 BC100948 AAI00949 BC114952 AAI14953 BC160088 AAI60088 NM_176881 NP_795362
|
Function |
Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity). {ECO:0000250}.
|
Subcellular Location |
Membrane; Multi-pass membrane protein.
|
Tissue Specificity |
Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells.
|
Top Pathways |
Taste transduction
|