Gene Symbol | TAS2R39 |
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Entrez Gene | 259285 |
Alt Symbol | T2R39, T2R57 |
Species | Human |
Gene Type | protein-coding |
Description | taste receptor, type 2, member 39 |
Other Description | taste receptor type 2 member 39|taste receptor type 2 member 57 |
Swissprots | Q3ZCN6 P59534 Q645W4 A4FUI7 |
Accessions | AAM19321 BAD98035 BAD98036 BAD98037 CAI53576 EAW51884 EAW51885 EAW51886 P59534 BC100947 AAI00948 BC100948 AAI00949 BC114952 AAI14953 BC160088 AAI60088 NM_176881 NP_795362 |
Function | Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity). {ECO:0000250}. |
Subcellular Location | Membrane; Multi-pass membrane protein. |
Tissue Specificity | Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells. |
Top Pathways | Taste transduction |
T2R39 CRISPR/Cas9 KO Plasmid (h) - sc-415265 from Santa Cruz Biotechnology
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T2R39 HDR Plasmid (h) - sc-415265-HDR from Santa Cruz Biotechnology
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T2R39 Double Nickase Plasmid (h) - sc-415265-NIC from Santa Cruz Biotechnology
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T2R39 Double Nickase Plasmid (h2) - sc-415265-NIC-2 from Santa Cruz Biotechnology
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T2R39 CRISPR Activation Plasmid (h) - sc-415265-ACT from Santa Cruz Biotechnology
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T2R39 CRISPR Activation Plasmid (h2) - sc-415265-ACT-2 from Santa Cruz Biotechnology
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T2R39 Lentiviral Activation Particles (h) - sc-415265-LAC from Santa Cruz Biotechnology
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T2R39 Lentiviral Activation Particles (h2) - sc-415265-LAC-2 from Santa Cruz Biotechnology
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T2R39 siRNA (h) - sc-89846 from Santa Cruz Biotechnology
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T2R39 shRNA Plasmid (h) - sc-89846-SH from Santa Cruz Biotechnology
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T2R39 shRNA (h) Lentiviral Particles - sc-89846-V from Santa Cruz Biotechnology
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TAS2R39 RNAi - H00259285-R02 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN21023 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21023 from Sigma-Aldrich
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TAS2R39 siRNA (Human) - CRJ6809 from Cohesion Biosciences
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TAS2R39 - MBS8225851 from MyBioSource
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shRNA set against Human TAS2R39 (NM_176881.2) - SHH423536 from Creative biogene
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Human TAS2R39 siRNA - orb277310 from Biorbyt
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TAS2R39 shRNA Plasmid (Human) - CHJ6809 from Cohesion Biosciences
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TAS2R39 miRNA 3'UTR clone - MiUTR1H-10196 from Creative biogene
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