IRF5
| Gene Symbol | IRF5 |
|---|---|
| Entrez Gene | 3663 |
| Alt Symbol | SLEB10 |
| Species | Human |
| Gene Type | protein-coding |
| Description | interferon regulatory factor 5 |
| Other Description | - |
| Swissprots | E7EQ16 Q6RCM8 Q1A7B4 Q64GB1 E7EW54 Q64GB2 Q9BQF0 A8DUA8 A4D1J8 Q64GA9 Q13568 A8DUA9 |
| Accessions | ABK41901 ABL96293 ABL96294 EAL24107 EAL24108 EAW83703 EAW83704 EAW83705 EAW83706 EAW83707 Q13568 AK293654 BAH11558 AK297083 BAG59600 AL713733 AY504946 AAR90325 AY504947 AAR90326 AY693665 AAU12877 AY693666 AAU12878 AY693667 AAU12879 AY693668 AAU12880 AY693669 AAU12881 BC004139 AAH04139 BC004201 AAH04201 BU540632 BU950658 CA427676 CA444548 DC427600 DQ277633 ABB88960 DQ277634 ABB88961 DQ893637 ABM84563 DQ995491 DQ995492 DQ995493 DQ995494 EU176684 ABW03485 EU258895 ABX54712 EU258896 ABX54713 EU258897 ABX54714 EU258898 ABX54715 JQ950681 AFN70752 JQ950682 AFN70753 JQ950683 AFN70754 JQ950684 AFN70755 JQ950685 AFN70756 U51127 AAA96056 XM_005250317 XP_005250374 XM_006715974 XP_006716037 XM_011516158 XP_011514460 XM_011516159 XP_011514461 XM_011516160 XP_011514462 XM_011516161 XP_011514463 XM_011516162 XP_011514464 XM_011516163 XP_011514465 XM_011516164 XP_011514466 NM_001098627 NP_001092097 NM_001098629 NP_001092099 NM_001098630 NP_001092100 NM_001242452 NP_001229381 NM_032643 NP_116032 |
| Function | Transcription factor involved in the induction of interferons IFNA and INFB and inflammatory cytokines upon virus infection. Activated by TLR7 or TLR8 signaling. {ECO:0000269|PubMed:11303025, ECO:0000269|PubMed:15695821}. |
| Subcellular Location | Cytoplasm. Nucleus. Note=Shuttles between the nucleus and the cytoplasm. |
| Top Pathways | Toll-like receptor signaling pathway |
IRF-5 CRISPR/Cas9 KO Plasmid (h) - sc-400920 from Santa Cruz Biotechnology
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IRF-5 HDR Plasmid (h) - sc-400920-HDR from Santa Cruz Biotechnology
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IRF-5 Double Nickase Plasmid (h) - sc-400920-NIC from Santa Cruz Biotechnology
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IRF-5 Double Nickase Plasmid (h2) - sc-400920-NIC-2 from Santa Cruz Biotechnology
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IRF-5 CRISPR Activation Plasmid (h) - sc-400920-ACT from Santa Cruz Biotechnology
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IRF-5 CRISPR Activation Plasmid (h2) - sc-400920-ACT-2 from Santa Cruz Biotechnology
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IRF-5 Lentiviral Activation Particles (h) - sc-400920-LAC from Santa Cruz Biotechnology
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IRF-5 Lentiviral Activation Particles (h2) - sc-400920-LAC-2 from Santa Cruz Biotechnology
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IRF-5 siRNA (h) - sc-72044 from Santa Cruz Biotechnology
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IRF-5 shRNA Plasmid (h) - sc-72044-SH from Santa Cruz Biotechnology
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IRF-5 shRNA (h) Lentiviral Particles - sc-72044-V from Santa Cruz Biotechnology
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IRF5 RNAi - H00003663-R02 from Novus Biologicals
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IRF5 RNAi - H00003663-R01 from Novus Biologicals
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MISSION® esiRNA - EHU140621 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN10767 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10767 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR12575 from Sigma-Aldrich
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IRF5 siRNA (Human) - CRH2456 from Cohesion Biosciences
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IRF5 - MBS8226660 from MyBioSource
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shRNA set against Human IRF5 (NM_001098629.1) - SHH320629 from Creative biogene
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shRNA set against Human IRF5(NM_032643.3) - SHL180888 from Creative biogene
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IRF5 shRNA Plasmid (Human) - CHH2456 from Cohesion Biosciences
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IRF5 miRNA 3'UTR clone - MiUTR1H-04994 from Creative biogene
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IRF5 miRNA 3'UTR clone - MiUTR3H-09055 from Creative biogene
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IRF5 miRNA 3'UTR clone - MiUTR3H-09056 from Creative biogene
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