Gene Symbol |
LAMA5
|
Entrez Gene |
3911
|
Alt Symbol |
-
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
laminin, alpha 5
|
Other Description |
laminin alpha-5 chain|laminin subunit alpha-5|laminin-10 subunit alpha|laminin-11 subunit alpha|laminin-15 subunit alpha
|
Swissprots |
Q9H1P1 Q8TDF8 Q5U4N9 Q8WZA7 O15230
|
Accessions |
CCQ43328 EAW75372 EAW75373 EAW75374 O15230 AB010099 BAA31347 AB011105 BAA25459 AB067494 BAB67800 AF443072 AAM12527 AK074307 BC003355 BC015386 BC085017 AAH85017 Z95636 CAB09137 XM_006723796 XP_006723859 XM_006723798 XP_006723861 XM_011528818 XP_011527120 XM_011528819 XP_011527121 XR_936532 NM_005560 NP_005551
|
Function |
Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.
|
Subcellular Location |
Secreted, extracellular space, extracellular matrix, basement membrane. Note=Major component.
|
Tissue Specificity |
Expressed in heart, lung, kidney, skeletal muscle, pancreas, retina and placenta. Little or no expression in brain and liver.
|
Top Pathways |
Focal adhesion, ECM-receptor interaction, Small cell lung cancer, Amoebiasis, Toxoplasmosis
|