Gene Symbol | LAMA5 |
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Entrez Gene | 3911 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | laminin, alpha 5 |
Other Description | laminin alpha-5 chain|laminin subunit alpha-5|laminin-10 subunit alpha|laminin-11 subunit alpha|laminin-15 subunit alpha |
Swissprots | Q9H1P1 Q8TDF8 Q5U4N9 Q8WZA7 O15230 |
Accessions | CCQ43328 EAW75372 EAW75373 EAW75374 O15230 AB010099 BAA31347 AB011105 BAA25459 AB067494 BAB67800 AF443072 AAM12527 AK074307 BC003355 BC015386 BC085017 AAH85017 Z95636 CAB09137 XM_006723796 XP_006723859 XM_006723798 XP_006723861 XM_011528818 XP_011527120 XM_011528819 XP_011527121 XR_936532 NM_005560 NP_005551 |
Function | Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. |
Subcellular Location | Secreted, extracellular space, extracellular matrix, basement membrane. Note=Major component. |
Tissue Specificity | Expressed in heart, lung, kidney, skeletal muscle, pancreas, retina and placenta. Little or no expression in brain and liver. |
Top Pathways | Focal adhesion, ECM-receptor interaction, Small cell lung cancer, Amoebiasis, Toxoplasmosis |
Laminin α-5 CRISPR/Cas9 KO Plasmid (h) - sc-401168 from Santa Cruz Biotechnology
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Laminin α-5 HDR Plasmid (h) - sc-401168-HDR from Santa Cruz Biotechnology
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Laminin α-5 Double Nickase Plasmid (h) - sc-401168-NIC from Santa Cruz Biotechnology
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Laminin α-5 Double Nickase Plasmid (h2) - sc-401168-NIC-2 from Santa Cruz Biotechnology
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Laminin α-5 CRISPR Activation Plasmid (h) - sc-401168-ACT from Santa Cruz Biotechnology
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Laminin α-5 CRISPR Activation Plasmid (h2) - sc-401168-ACT-2 from Santa Cruz Biotechnology
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Laminin α-5 Lentiviral Activation Particles (h) - sc-401168-LAC from Santa Cruz Biotechnology
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Laminin α-5 Lentiviral Activation Particles (h2) - sc-401168-LAC-2 from Santa Cruz Biotechnology
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Laminin α-5 siRNA (h) - sc-43149 from Santa Cruz Biotechnology
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Laminin α-5 shRNA Plasmid (h) - sc-43149-SH from Santa Cruz Biotechnology
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Laminin α-5 shRNA (h) Lentiviral Particles - sc-43149-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU074291 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN11530 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11530 from Sigma-Aldrich
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LAMA5 siRNA (Human) - CRH2650 from Cohesion Biosciences
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Laminin alpha 5 RNAi - H00003911-R01 from Novus Biologicals
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shRNA set against Human LAMA5 (NM_005560.3) - SHH328247 from Creative biogene
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shRNA set against Human LAMA5(NM_005560.3) - SHH141473 from Creative biogene
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Human LAMA5 siRNA - orb263152 from Biorbyt
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LAMA5 shRNA Plasmid (Human) - CHH2650 from Cohesion Biosciences
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LAMA5 miRNA 3'UTR clone - MiUTR1H-05559 from Creative biogene
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