Gene Symbol | BCHE |
---|---|
Entrez Gene | 590 |
Alt Symbol | CHE1, CHE2, E1 |
Species | Human |
Gene Type | protein-coding |
Description | butyrylcholinesterase |
Other Description | acylcholine acylhydrolase|butyrylcholine esterase|choline esterase II|cholinesterase|cholinesterase (serum) 2|cholinesterase 1|pseudocholinesterase |
Swissprots | P06276 A8K7P8 |
Accessions | AAA99296 AHZ34326 AHZ34327 EAW78591 EAW78592 EAW78593 EAW78594 P06276 AK292063 BAF84752 BC008396 AAH08396 BC018141 AAH18141 BF056152 DA426203 DQ891041 ABM81967 DQ894220 ABM85146 M16474 AAA52015 M16541 AAA98113 XM_005247685 XP_005247742 NM_000055 NP_000046 |
Function | Esterase with broad substrate specificity. Contributes to the inactivation of the neurotransmitter acetylcholine. Can degrade neurotoxic organophosphate esters. {ECO:0000269|PubMed:19452557, ECO:0000269|PubMed:19542320}. |
Subcellular Location | Secreted {ECO:0000269|PubMed:19368529, ECO:0000269|PubMed:19542320}. |
Tissue Specificity | Detected in blood plasma (at protein level). Present in most cells except erythrocytes. {ECO:0000269|PubMed:19368529, ECO:0000269|PubMed:19542320}. |