Gene Symbol | BCHE |
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Entrez Gene | 590 |
Alt Symbol | CHE1, CHE2, E1 |
Species | Human |
Gene Type | protein-coding |
Description | butyrylcholinesterase |
Other Description | acylcholine acylhydrolase|butyrylcholine esterase|choline esterase II|cholinesterase|cholinesterase (serum) 2|cholinesterase 1|pseudocholinesterase |
Swissprots | P06276 A8K7P8 |
Accessions | AAA99296 AHZ34326 AHZ34327 EAW78591 EAW78592 EAW78593 EAW78594 P06276 AK292063 BAF84752 BC008396 AAH08396 BC018141 AAH18141 BF056152 DA426203 DQ891041 ABM81967 DQ894220 ABM85146 M16474 AAA52015 M16541 AAA98113 XM_005247685 XP_005247742 NM_000055 NP_000046 |
Function | Esterase with broad substrate specificity. Contributes to the inactivation of the neurotransmitter acetylcholine. Can degrade neurotoxic organophosphate esters. {ECO:0000269|PubMed:19452557, ECO:0000269|PubMed:19542320}. |
Subcellular Location | Secreted {ECO:0000269|PubMed:19368529, ECO:0000269|PubMed:19542320}. |
Tissue Specificity | Detected in blood plasma (at protein level). Present in most cells except erythrocytes. {ECO:0000269|PubMed:19368529, ECO:0000269|PubMed:19542320}. |
BChE CRISPR/Cas9 KO Plasmid (h) - sc-401834 from Santa Cruz Biotechnology
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BChE HDR Plasmid (h) - sc-401834-HDR from Santa Cruz Biotechnology
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BChE Double Nickase Plasmid (h) - sc-401834-NIC from Santa Cruz Biotechnology
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BChE Double Nickase Plasmid (h2) - sc-401834-NIC-2 from Santa Cruz Biotechnology
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BChE CRISPR Activation Plasmid (h) - sc-401834-ACT from Santa Cruz Biotechnology
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BChE CRISPR Activation Plasmid (h2) - sc-401834-ACT-2 from Santa Cruz Biotechnology
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BChE Lentiviral Activation Particles (h) - sc-401834-LAC from Santa Cruz Biotechnology
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BChE Lentiviral Activation Particles (h2) - sc-401834-LAC-2 from Santa Cruz Biotechnology
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BChE siRNA (h) - sc-60267 from Santa Cruz Biotechnology
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BChE shRNA Plasmid (h) - sc-60267-SH from Santa Cruz Biotechnology
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BChE shRNA (h) Lentiviral Particles - sc-60267-V from Santa Cruz Biotechnology
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Butyrylcholinesterase/BCHE RNAi - H00000590-R01 from Novus Biologicals
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MISSION® esiRNA - EHU001231 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN3900 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3900 from Sigma-Aldrich
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BCHE siRNA (Human) - CRH0405 from Cohesion Biosciences
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BCHE - MBS8202563 from MyBioSource
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shRNA set against Human BCHE (NM_000055.2) - SHH245798 from Creative biogene
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shRNA set against Human BCHE(NM_000055.2) - SHG096631 from Creative biogene
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BCHE shRNA Plasmid (Human) - CHH0405 from Cohesion Biosciences
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BCHE miRNA 3'UTR clone - MiUTR1H-00833 from Creative biogene
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