MAEA

Gene Symbol MAEA
Entrez Gene 10296
Alt Symbol EMLP, EMP, GID9, HLC-10, PIG5
Species Human
Gene Type protein-coding
Description macrophage erythroblast attacher
Other Description GID complex subunit 9, FYV10 homolog|cell proliferation-inducing gene 5 protein|erythroblast macrophage protein|human lung cancer oncogene 10 protein|lung cancer-related protein 10
Swissprots Q9BQ11 Q9NW84 Q5JB54 Q9H9V6 Q9H9Z4 Q7L5Y9 O95285 Q6ZRD6
Accessions EAW82586 EAW82587 EAW82588 EAW82589 EAW82590 EAW82591 EAW82592 EAW82593 EAW82594 EAW82595 EAW82596 Q7L5Y9 AB208907 BAD92144 AF084928 AAC67543 AK001088 BAA91499 AK022515 BAB14072 AK022586 BAB14113 AK091951 BAG52449 AK094253 AK125501 AK127875 BAG54590 AK128302 AK296174 BAG58910 AK298944 BAG61043 AK300572 BAG62274 AK301155 BAG62745 AK308901 AY189687 AAO85220 AY236486 AAP74806 BC001225 AAH01225 BC006470 AAH06470 BT006957 AAP35603 BU607457 DC299400 DC331820 DC400017 XM_005272247 XP_005272304 XM_006713849 XP_006713912 XM_006713850 XP_006713913 XM_011513376 XP_011511678 XM_011513377 XP_011511679 XM_011513378 XP_011511680 XM_011513379 XP_011511681 XM_011513380 XP_011511682 XR_924910 NM_001017405 NP_001017405 NM_001297430 NP_001284359 NM_001297431 NP_001284360 NM_001297432 NP_001284361 NM_001297433 NP_001284362 NM_005882 NP_005873 NR_123716
Function Plays a role in erythroblast enucleation and in the development of the mature macrophages. Mediates the attachment of erythroid cell to mature macrophages, in correlation with the presence of MAEA at cell surface of mature macrophages; This MAEA- mediated contact inhibits erythroid cells apoptosis. Participates to erythroblastic island formation, which is the functional unit of definitive erythropoiesis. Associates with F-actin to regulate actin distribution in erythroblasts and macrophages. May contribute to nuclear architecture and cells division events. {ECO:0000269|PubMed:16510120, ECO:0000269|PubMed:9763581}.
Subcellular Location Nucleus matrix {ECO:0000269|PubMed:16510120}. Cell membrane {ECO:0000269|PubMed:16510120}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:16510120}. Note=Localized as nuclear speckled- like pattern.
Tissue Specificity Ubiquitous. {ECO:0000269|PubMed:16510120, ECO:0000269|PubMed:9763581}.

Emp CRISPR/Cas9 KO Plasmid (h) - sc-407482 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Emp HDR Plasmid (h) - sc-407482-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Emp Double Nickase Plasmid (h) - sc-407482-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Emp Double Nickase Plasmid (h2) - sc-407482-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Emp CRISPR Activation Plasmid (h) - sc-407482-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Emp CRISPR Activation Plasmid (h2) - sc-407482-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Emp Lentiviral Activation Particles (h) - sc-407482-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Emp Lentiviral Activation Particles (h2) - sc-407482-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Emp siRNA (h) - sc-89290 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Emp shRNA Plasmid (h) - sc-89290-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Emp shRNA (h) Lentiviral Particles - sc-89290-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU065961 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN12898 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND12898 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR07818 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr07818

MAEA siRNA (Human) - CRH6976 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human MAEA(NM_001017405.1) - SHH170003 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human MAEA(NM_005882.3) - SHH170039 from Creative biogene

Category siRNA
Species Reactivities Human

Human MAEA siRNA - orb267478 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

MAEA shRNA Plasmid (Human) - CHH6976 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

MAEA miRNA 3'UTR clone - MiUTR1H-05997 from Creative biogene

Species Reactivities Human

MAEA miRNA 3'UTR clone - MiUTR1H-05998 from Creative biogene

Species Reactivities Human
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