| Gene Symbol |
MMP20
|
| Entrez Gene |
9313
|
| Alt Symbol |
AI2A2, MMP-20
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
matrix metallopeptidase 20
|
| Other Description |
enamel metalloproteinase|matrix metalloproteinase 20 (enamelysin)|matrix metalloproteinase-20
|
| Swissprots |
O60882 Q6DKT9
|
| Accessions |
AAT70722 EAW67024 O60882 AJ296177 CAC14668 BC152741 AAI52742 Y12779 CAA73317 NM_004771 NP_004762
|
| Function |
Degrades amelogenin, the major protein component of the enamel matrix and two of the macromolecules characterizing the cartilage extracellular matrix: aggrecan and the cartilage oligomeric matrix protein (COMP). May play a central role in tooth enamel formation. {ECO:0000269|PubMed:10922468, ECO:0000269|PubMed:9398237}.
|
| Subcellular Location |
Secreted, extracellular space, extracellular matrix {ECO:0000250}.
|
| Tissue Specificity |
Expressed specifically in the enamel organ.
|
![Western Blot: MMP20 Overexpression Lysate (Adult Normal) [NBL1-13156] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for MMP20.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/5620_MMP20%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-13156-img0002.jpg)