Gene Symbol | MMP20 |
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Entrez Gene | 9313 |
Alt Symbol | AI2A2, MMP-20 |
Species | Human |
Gene Type | protein-coding |
Description | matrix metallopeptidase 20 |
Other Description | enamel metalloproteinase|matrix metalloproteinase 20 (enamelysin)|matrix metalloproteinase-20 |
Swissprots | O60882 Q6DKT9 |
Accessions | AAT70722 EAW67024 O60882 AJ296177 CAC14668 BC152741 AAI52742 Y12779 CAA73317 NM_004771 NP_004762 |
Function | Degrades amelogenin, the major protein component of the enamel matrix and two of the macromolecules characterizing the cartilage extracellular matrix: aggrecan and the cartilage oligomeric matrix protein (COMP). May play a central role in tooth enamel formation. {ECO:0000269|PubMed:10922468, ECO:0000269|PubMed:9398237}. |
Subcellular Location | Secreted, extracellular space, extracellular matrix {ECO:0000250}. |
Tissue Specificity | Expressed specifically in the enamel organ. |
MMP-20 CRISPR/Cas9 KO Plasmid (h) - sc-405838 from Santa Cruz Biotechnology
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MMP-20 HDR Plasmid (h) - sc-405838-HDR from Santa Cruz Biotechnology
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MMP-20 Double Nickase Plasmid (h) - sc-405838-NIC from Santa Cruz Biotechnology
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MMP-20 Double Nickase Plasmid (h2) - sc-405838-NIC-2 from Santa Cruz Biotechnology
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MMP-20 CRISPR Activation Plasmid (h) - sc-405838-ACT from Santa Cruz Biotechnology
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MMP-20 CRISPR Activation Plasmid (h2) - sc-405838-ACT-2 from Santa Cruz Biotechnology
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MMP-20 Lentiviral Activation Particles (h) - sc-405838-LAC from Santa Cruz Biotechnology
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MMP-20 Lentiviral Activation Particles (h2) - sc-405838-LAC-2 from Santa Cruz Biotechnology
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MMP-20 siRNA (h) - sc-41561 from Santa Cruz Biotechnology
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MMP-20 shRNA Plasmid (h) - sc-41561-SH from Santa Cruz Biotechnology
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MMP-20 shRNA (h) Lentiviral Particles - sc-41561-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU001641 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN2240 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2240 from Sigma-Aldrich
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MMP20 siRNA (Human) - CRH6160 from Cohesion Biosciences
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MMP-20 CRISPR/Cas9 KO Plasmid (h2) - sc-405838-KO-2 from Santa Cruz Biotechnology
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MMP-20 HDR Plasmid (h2) - sc-405838-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human MMP20 (NM_004771.3) - SHH343000 from Creative biogene
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shRNA set against Human MMP20(NM_004771.3) - SHH193745 from Creative biogene
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Human MMP20 siRNA - orb266662 from Biorbyt
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MMP20 shRNA Plasmid (Human) - CHH6160 from Cohesion Biosciences
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MMP20 miRNA 3'UTR clone - MiUTR1H-06352 from Creative biogene
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