Gene Symbol | EPX |
---|---|
Entrez Gene | 8288 |
Alt Symbol | EPO, EPP, EPX-PEN |
Species | Human |
Gene Type | protein-coding |
Description | eosinophil peroxidase |
Other Description | - |
Swissprots | Q4TVP3 P11678 |
Accessions | AAA58458 AAY43126 EAW94479 EAW94480 P11678 AJ705406 AL597635 BC111602 AAI11603 BM147889 X14346 CAA32530 NM_000502 NP_000493 |
Function | Mediates tyrosine nitration of secondary granule proteins in mature resting eosinophils. Shows significant inhibitory activity towards Mycobacterium tuberculosis H37Rv by inducing bacterial fragmentation and lysis. {ECO:0000269|PubMed:12540536, ECO:0000269|PubMed:18694936}. |
Subcellular Location | Cytoplasmic granule. Note=Cytoplasmic granules of eosinophils. |
Top Pathways | Asthma |