| Gene Symbol |
CASP2
|
| Entrez Gene |
835
|
| Alt Symbol |
CASP-2, ICH1, NEDD-2, NEDD2, PPP1R57
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
caspase 2, apoptosis-related cysteine peptidase
|
| Other Description |
caspase-2|neural precursor cell expressed developmentally down-regulated protein 2|protease ICH-1|protein phosphatase 1, regulatory subunit 57
|
| Swissprots |
Q59F21 Q9BZL0 D3DXD6 Q9BZK9 E9PDN0 A8K5F9 Q9BUP7 P42575 Q7KZL6 P42576 Q86UJ3
|
| Accessions |
AAO25653 AAP22346 AAP22347 AAP22348 AAP22349 EAW51860 EAW51862 EAW51863 EAW51864 EAW51867 EAW51869 EAW51870 P42575 AB209640 BAD92877 AF314174 AAK00299 AF314175 AAK00300 AK096245 AK291274 BAF83963 AK303265 BAG64347 AK303391 BAG64447 BC002427 AAH02427 BG397039 BM998653 BQ447606 BT007240 AAP35904 BX537669 CB988674 CR541748 CAG46548 DA505883 DB455837 DB455840 DQ893820 ABM84746 U13021 AAA58959 U13022 AAA58960 NM_001224 NP_001215 NM_032982 NP_116764 NM_032983 NP_116765
|
| Function |
Involved in the activation cascade of caspases responsible for apoptosis execution. Might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival.
|
| Tissue Specificity |
Expressed at higher levels in the embryonic lung, liver and kidney than in the heart and brain. In adults, higher level expression is seen in the placenta, lung, kidney, and pancreas than in the heart, brain, liver and skeletal muscle.
|