| Gene Symbol |
ST3GAL5
|
| Entrez Gene |
8869
|
| Alt Symbol |
SATI, SIAT9, SIATGM3S, ST3GalV
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
|
| Other Description |
CMP-NeuAc:lactosylceramide alpha-2,3-sialyltransferase|GM3 synthase|ST3Gal V|alpha 2,3-sialyltransferase V|ganglioside GM3 synthase|lactosylceramide alpha-2,3-sialyltransferase|sialyltransferase 9 (CMP-NeuAc:lactosylceramide alpha-2,3-sialyltransferase; GM3 synthase)
|
| Swissprots |
Q6YFL1 Q6NZX4 O94902 D6W5L9 Q9UNP4 Q53QU1 B3KM82
|
| Accessions |
AAY24147 EAW99474 EAW99475 EAW99476 EAW99477 EAW99478 EAW99479 EAW99480 Q9UNP4 AB018356 BAA33950 AF105026 AAD14634 AF119415 AAF66146 AF119417 AF119418 AF161396 AAF28956 AF344831 AK001340 BAG50894 AK124862 BAC85970 AK127346 AK295252 BAH12019 AK315955 BAH14326 AY152815 AAO16866 AY359105 AAQ89463 BC009887 BC065936 AAH65936 BI820835 CA503200 XM_005264630 XP_005264687 XM_011533143 XP_011531445 XR_939734 XR_939735 XR_939736 NM_001042437 NP_001035902 NM_003896 NP_003887
|
| Function |
Catalyzes the formation of ganglioside GM3 (alpha-N- acetylneuraminyl-2,3-beta-D-galactosyl-1, 4-beta-D- glucosylceramide). {ECO:0000269|PubMed:16934889}.
|
| Subcellular Location |
Golgi apparatus membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
|
| Tissue Specificity |
Ubiquitous. High expression in brain, skeletal muscle, placenta, and testis.
|
| Top Pathways |
Glycosphingolipid biosynthesis - ganglio series
|