Gene Symbol | Prdx1 |
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Entrez Gene | 18477 |
Alt Symbol | MSP23, NkefA, OSF-3, OSF3, PAG, Paga, PrdxI, PrxI, TDX2, TPxA, Tdpx2, prx1 |
Species | Mouse |
Gene Type | protein-coding |
Description | peroxiredoxin 1 |
Other Description | Trx dependent peroxide reductase 2|macrophage 23 Kd stress protein|macrophage 23 kDa stress protein|macrophage 23kDa stress protein|macrophase stress protein 22kDa|macrophase stress protein 23 kd|osteoblast specific factor 3|osteoblast-specific factor 3|peroxiredoxin-1|proliferation-associated gene A|thioredoxin dependent peroxide reductase 2|thioredoxin peroxidase 2|thioredoxin-dependent peroxide reductase 2 |
Swissprots | Q9CWI2 Q3UBV4 P35700 |
Accessions | AAD45323 BAA86992 EDL30594 P35700 AK002287 BAB21990 AK008711 BAB25847 AK010688 BAB27120 AK083243 BAC38827 AK145138 BAE26255 AK150797 BAE29860 AK151459 BAE30417 AK151760 BAE30667 AK163984 AK167624 BAE39676 AK169154 BAE40933 AK169992 AK184215 AK184318 BC083348 AAH83348 BC086648 AAH86648 D16142 BAA03713 D21252 BAA04796 NM_011034 NP_035164 |
Function | Involved in redox regulation of the cell. Reduces peroxides with reducing equivalents provided through the thioredoxin system but not from glutaredoxin. May play an important role in eliminating peroxides generated during metabolism. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2). Regulates GDPD5 function by reducing an intramolecular disulfide bond (By similarity). Cooperates with GDPD5 to drive postmitotic motor neuron differentiation. {ECO:0000250, ECO:0000269|PubMed:19766572}. |
Subcellular Location | Cytoplasm. Melanosome {ECO:0000250}. |
Tissue Specificity | Found in various tissues; high concentration in liver. |
Top Pathways | Peroxisome |
Mouse PRDX1 His tag protein - orb84711 from Biorbyt
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Mouse Peroxiredoxin 1 Protein - abx068476 from Abbexa
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Peroxiredoxin 1 (PRDX1), Mouse - 20-8572 from ARP American Research Products
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Recombinant Mouse Prdx1, His tagged - Prdx1-2544M from Creative Biomart
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Mouse Peroxiredoxin 1 / PRDX1 Protein (His Tag) - 50552-M08E-20 from Sino Biological
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Recombinant Peroxiredoxin 1 (PRDX1) - RPC749Mu01 from Cloud-clone
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Recombinant Peroxiredoxin 1 (PRDX1) - RPC749Mu02 from Cloud-clone
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Recombinant Mouse Peroxiredoxin-1(Prdx1) - CSB-YP018653MO CSB-EP018653MO CSB-BP018653MO CSB-MP018653MO from Cusabio
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Peroxiredoxin 1 (PRDX1) - RPU143230 from Biomatik
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Peroxiredoxin 1 (PRDX1), Recombinant Protein - MBS2011484 from MyBioSource
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Peroxiredoxin-1 (Prdx1), Recombinant Protein - MBS968618 from MyBioSource
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Recombinant Mouse Peroxiredoxin 1 / PRDX1 Protein (His tag) - PKSM040618 from Elabscience
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Prdx1, 1-199aa, Mouse, His tag, Baculovirus (Bioactivity Validated) - ATGP3340 from ATGen
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Peroxiredoxin-1 / PRDX1 (1-199, His-tag) - AR52067PU-N from Acris Antibodies
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Peroxiredoxin-1 / PRDX1 (1-199, His-tag) - AR52067PU-S from Acris Antibodies
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Peroxiredoxin-1, Mouse Recombinant - 228-20895-1 from RayBiotech
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Prdx1 - PAT-83545-1 from Nordic BioSite
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Prdx1 - PAT-83545-2 from Nordic BioSite
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Recombinant Peroxiredoxin 1 (PRDX1) - RPU43230 from Biomatik
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PRDX1 Recombinant Protein (OPCD06373) - OPCD06373 from Aviva Systems Biology
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Mouse Peroxiredoxin 1 / PRDX1 Protein (His Tag) - 50552-M08E from ABclonal
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Peroxiredoxin 1 / PRDX1, Recombinant Protein - MBS2546919 from MyBioSource
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Peroxiredoxin-1, Recombinant Protein - MBS146799 from MyBioSource
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Prdx1, Recombinant Protein - MBS206323 from MyBioSource
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