Gene Symbol | ATXN7L3 |
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Entrez Gene | 56970 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | ataxin 7-like 3 |
Other Description | ataxin-7-like protein 3 |
Swissprots | Q96N40 Q8IY68 Q14CW9 Q9NPU5 |
Accessions | CCQ43629 EAW51622 Q14CW9 AK056002 BAB71070 AK074344 AK126117 AK296689 BAG59283 AL390158 CAB99093 BC024695 BC037418 AAH37418 BC064932 BC100295 BC113595 AAI13596 BC126113 AAI26114 DQ588490 HQ258188 ADR82942 XM_011525036 XP_011523338 XM_011525037 XP_011523339 XM_011525038 XP_011523340 XM_011525039 XP_011523341 XM_011525040 XP_011523342 XM_011525041 XP_011523343 XM_011525042 XP_011523344 XM_011525043 XP_011523345 XM_011525044 XP_011523346 XM_011525045 XP_011523347 XM_011525046 XP_011523348 XM_011525047 XP_011523349 NM_001098833 NP_001092303 NM_020218 NP_064603 |
Function | Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and ENY2 into the SAGA complex. {ECO:0000255|HAMAP- Rule:MF_03047, ECO:0000269|PubMed:18206972, ECO:0000269|PubMed:21746879}. |
Subcellular Location | Nucleus {ECO:0000255|HAMAP-Rule:MF_03047}. |
ATXN7L3 (C-16) - sc-241880 from Santa Cruz Biotechnology
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ATXN7L3 (Q-20) - sc-241879 from Santa Cruz Biotechnology
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Anti-ATXN7L3 antibody - ab185197 from Abcam
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Anti-ATXN7L3 antibody - ab176779 from Abcam
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Anti-ATXN7L3 Antibody (aa297-347) - LS-C289512 from LifeSpan Bioscience
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Anti-ATXN7L3 Antibody (aa126-175) - LS-C169856 from LifeSpan Bioscience
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Ataxin 7-Like 3 Antibody - NBP2-30710 from Novus Biologicals
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Anti-ATXN7L3 antibody produced in rabbit - HPA050625 from Sigma-Aldrich
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ATXN7L3 Antibody - middle region (ARP67018_P050) - ARP67018_P050 from Aviva Systems Biology
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ATXN7L3 antibody - GTX122602 from GeneTex
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Ataxin 7L3 Antibody - abx121023 from Abbexa
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ATXN7L3 Antibody - abx037189 from Abbexa
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ATXN7L3 antibody - H00056970-B01P from Acris Antibodies
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ATXN7L3 Antibody - E307176 from Enogene
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Atxn7l3 antibody (mAb) - 61339 from ActiveMotif
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ATXN7L3 - MBS276741 from MyBioSource
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Anti-ATXN7L3 (aa 1-174) polyclonal antibody - DPABH-04713 from Creative Diagnostics
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Anti-ATXN7L3 (aa 2-189) polyclonal antibody - DPABH-12100 from Creative Diagnostics
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Anti-ATXN7L3 (aa 126-197) polyclonal antibody - DPABH-14754 from Creative Diagnostics
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Anti-ATXN7L3 (aa 126-175) polyclonal antibody - DPABH-26884 from Creative Diagnostics
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ATXN7L3 Antibody - A302-800A from Bethyl Labs
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ATXN7L3 Polyclonal Antibody - PA5-32017 from Thermo Fisher Scientific
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Anti-Ataxin 7L3 Antibody - CPA3522 from Cohesion Biosciences
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ATXN7L3 polyclonal antibody - BS60601 from Bioworld Technology
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Anti-ATXN7L3 Antibody (Internal) - LS-C354279 from LifeSpan Bioscience
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