Gene Symbol |
CSTF2
|
Entrez Gene |
1478
|
Alt Symbol |
CstF-64
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa
|
Other Description |
CF-1 64 kDa subunit|CSTF 64 kDa subunit|betaCstF-64 variant 2|cleavage stimulation factor 64 kDa subunit|cleavage stimulation factor subunit 2|cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kD
|
Swissprots |
Q6LA74 P33240 Q8N502 Q5H951
|
Accessions |
EAX02818 EAX02819 P33240 AI826277 AK095684 AK300600 BAG62297 AW016125 BC017712 AAH17712 BC033135 AAH33135 BT009778 AAP88780 BX384743 DQ891532 ABM82458 DQ894721 ABM85647 EU616679 ACF05699 M85085 AAA35724 XM_011530873 XP_011529175 XM_011530874 XP_011529176 NM_001306206 NP_001293135 NM_001306209 NP_001293138 NM_001325 NP_001316
|
Function |
One of the multiple factors required for polyadenylation and 3'-end cleavage of mammalian pre-mRNAs. This subunit is directly involved in the binding to pre-mRNAs (By similarity). {ECO:0000250}.
|
Subcellular Location |
Nucleus {ECO:0000269|PubMed:11598190}. Note=Localized with DDX1 in cleavage bodies.
|
Top Pathways |
mRNA surveillance pathway
|