Gene Symbol | CSTF2 |
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Entrez Gene | 1478 |
Alt Symbol | CstF-64 |
Species | Human |
Gene Type | protein-coding |
Description | cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa |
Other Description | CF-1 64 kDa subunit|CSTF 64 kDa subunit|betaCstF-64 variant 2|cleavage stimulation factor 64 kDa subunit|cleavage stimulation factor subunit 2|cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kD |
Swissprots | Q6LA74 P33240 Q8N502 Q5H951 |
Accessions | EAX02818 EAX02819 P33240 AI826277 AK095684 AK300600 BAG62297 AW016125 BC017712 AAH17712 BC033135 AAH33135 BT009778 AAP88780 BX384743 DQ891532 ABM82458 DQ894721 ABM85647 EU616679 ACF05699 M85085 AAA35724 XM_011530873 XP_011529175 XM_011530874 XP_011529176 NM_001306206 NP_001293135 NM_001306209 NP_001293138 NM_001325 NP_001316 |
Function | One of the multiple factors required for polyadenylation and 3'-end cleavage of mammalian pre-mRNAs. This subunit is directly involved in the binding to pre-mRNAs (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:11598190}. Note=Localized with DDX1 in cleavage bodies. |
Top Pathways | mRNA surveillance pathway |
CstF-64 CRISPR/Cas9 KO Plasmid (h) - sc-402202 from Santa Cruz Biotechnology
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CstF-64 HDR Plasmid (h) - sc-402202-HDR from Santa Cruz Biotechnology
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CstF-64 Double Nickase Plasmid (h) - sc-402202-NIC from Santa Cruz Biotechnology
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CstF-64 Double Nickase Plasmid (h2) - sc-402202-NIC-2 from Santa Cruz Biotechnology
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CstF-64 CRISPR Activation Plasmid (h) - sc-402202-ACT from Santa Cruz Biotechnology
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CstF-64 CRISPR Activation Plasmid (h2) - sc-402202-ACT-2 from Santa Cruz Biotechnology
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CstF-64 Lentiviral Activation Particles (h) - sc-402202-LAC from Santa Cruz Biotechnology
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CstF-64 Lentiviral Activation Particles (h2) - sc-402202-LAC-2 from Santa Cruz Biotechnology
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CstF-64 siRNA (h) - sc-35118 from Santa Cruz Biotechnology
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CstF-64 shRNA Plasmid (h) - sc-35118-SH from Santa Cruz Biotechnology
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CstF-64 shRNA (h) Lentiviral Particles - sc-35118-V from Santa Cruz Biotechnology
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Cleavage stimulation factor 2 RNAi - H00001478-R01 from Novus Biologicals
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MISSION® esiRNA - EHU003141 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN6683 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6683 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR01391 from Sigma-Aldrich
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CSTF2 siRNA (Human) - CRH1046 from Cohesion Biosciences
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CSTF2 - MBS8204723 from MyBioSource
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shRNA set against Human CSTF2 (NM_001325.2) - SHH270853 from Creative biogene
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shRNA set against Human CSTF2(NM_001325.2) - SHG205387 from Creative biogene
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CSTF2 shRNA Plasmid (Human) - CHH1046 from Cohesion Biosciences
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CSTF2 miRNA 3'UTR clone - MiUTR1H-02499 from Creative biogene
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