| Gene Symbol |
Cdx2
|
| Entrez Gene |
12591
|
| Alt Symbol |
Cdx-2
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
caudal type homeobox 2
|
| Other Description |
caudal type homeo box 2|caudal-type homeobox protein 2|homeobox protein CDX-2
|
| Swissprots |
P43241
|
| Accessions |
AAA19645 EDL05830 P43241 AK018629 AK049566 BAC33814 AK049574 BAC33820 BC103516 AAI03517 BC103517 AAI03518 BC103519 AAI03520 BC103520 AAI03521 S74520 AAB32251 NM_007673 NP_031699
|
| Function |
Involved in the transcriptional regulation of multiple genes expressed in the intestinal epithelium. Important in broad range of functions from early differentiation to maintenance of the intestinal epithelial lining of both the small and large intestine.
|
| Subcellular Location |
Nucleus.
|
| Tissue Specificity |
Intestine; expressed specifically in gut epithelium where it is not restricted to a particular cell lineage. Abundant expression is seen in the proximal colon with slightly lower levels in distal colon. Expression in the proximal colon is not restricted either to a particular cell lineage or stage of differentiation while in the distal colon it is more abundant in the differentiated cells towards the top of the crypt.
|