Gene Symbol | Cdx2 |
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Entrez Gene | 12591 |
Alt Symbol | Cdx-2 |
Species | Mouse |
Gene Type | protein-coding |
Description | caudal type homeobox 2 |
Other Description | caudal type homeo box 2|caudal-type homeobox protein 2|homeobox protein CDX-2 |
Swissprots | P43241 |
Accessions | AAA19645 EDL05830 P43241 AK018629 AK049566 BAC33814 AK049574 BAC33820 BC103516 AAI03517 BC103517 AAI03518 BC103519 AAI03520 BC103520 AAI03521 S74520 AAB32251 NM_007673 NP_031699 |
Function | Involved in the transcriptional regulation of multiple genes expressed in the intestinal epithelium. Important in broad range of functions from early differentiation to maintenance of the intestinal epithelial lining of both the small and large intestine. |
Subcellular Location | Nucleus. |
Tissue Specificity | Intestine; expressed specifically in gut epithelium where it is not restricted to a particular cell lineage. Abundant expression is seen in the proximal colon with slightly lower levels in distal colon. Expression in the proximal colon is not restricted either to a particular cell lineage or stage of differentiation while in the distal colon it is more abundant in the differentiated cells towards the top of the crypt. |
Cdx2 CRISPR/Cas9 KO Plasmid (m) - sc-419618 from Santa Cruz Biotechnology
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Cdx2 HDR Plasmid (m) - sc-419618-HDR from Santa Cruz Biotechnology
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Cdx2 Double Nickase Plasmid (m) - sc-419618-NIC from Santa Cruz Biotechnology
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Cdx2 Double Nickase Plasmid (m2) - sc-419618-NIC-2 from Santa Cruz Biotechnology
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Cdx2 CRISPR Activation Plasmid (m) - sc-419618-ACT from Santa Cruz Biotechnology
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Cdx2 CRISPR Activation Plasmid (m2) - sc-419618-ACT-2 from Santa Cruz Biotechnology
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Cdx2 Lentiviral Activation Particles (m) - sc-419618-LAC from Santa Cruz Biotechnology
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Cdx2 Lentiviral Activation Particles (m2) - sc-419618-LAC-2 from Santa Cruz Biotechnology
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Cdx2 siRNA (m) - sc-142243 from Santa Cruz Biotechnology
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Cdx2 shRNA Plasmid (m) - sc-142243-SH from Santa Cruz Biotechnology
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Cdx2 shRNA (m) Lentiviral Particles - sc-142243-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU002731 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN28527 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND28527 from Sigma-Aldrich
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CDX2 siRNA (Mouse) - CRM0659 from Cohesion Biosciences
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CDX2 - MBS829422 from MyBioSource
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shRNA set against Mouse CDX2 (NM_007673.3) - SHH261085 from Creative biogene
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shRNA set against Mouse Cdx2(NM_007673.3) - SHG166285 from Creative biogene
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Mouse CDX2 siRNA - orb280135 from Biorbyt
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CDX2 shRNA Plasmid (Mouse) - CHM0659 from Cohesion Biosciences
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CDX2 miRNA 3'UTR clone - MiUTR1M-02894 from Creative biogene
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